Compounds > t 30177
Page last updated: 2024-11-12

t 30177

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

T 30177: an oligonucleotide composed of only deoxyguanosine and thymidine; 17 nucleotides long; contains single phosphorothioate internucleoside linkages at its 5' and 3' ends; nucleotide sequence given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID16129728
MeSH IDM0257911

Synonyms (8)

Synonym
dna, d(g-sp-t-g-g-t-g-g-g-t-g-g-g-t-g-g-g-sp-t)
t 30177
163703-74-0
dna, d(p-thio)(g-t-g-g-t-g-g-g-t-g-g-g-t-g-g-g-t)
deoxyribonucleic acid, d(p-thio)(g-t-g-g-t-g-g-g-t-g-g-g-t-g-g-g-t)
ar-177 free acid
unii-rr07n525h5
rr07n525h5 ,
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (17)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's9 (52.94)18.2507
2000's6 (35.29)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.29

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.29 (24.57)
Research Supply Index2.89 (2.92)
Research Growth Index4.18 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.29)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (11.76%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other15 (88.24%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
cordycepin
[no description available]		1.99103'-deoxyribonucleoside;
adenosines		antimetabolite;
nucleoside antibiotic
hydrazine
diamine : Any polyamine that contains two amino groups.		210azane;
hydrazines		EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
manganese
Manganese: A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035). manganese(4+) : A manganese cation that is monoatomic and has a formal charge of +4.		1.9910elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient
chicoric acid
chicoric acid: inhibits HIV-1 integrase		3.1110organooxygen compoundgeroprotector;
HIV-1 integrase inhibitor
gem91
GEM91: a 25-mer antisense oligonucleotide phosphorothioate used as a therapeutic agents for AIDS; may block the translation of gag mRNA& disrupt the secondary structure of RNA		3.110
oligonucleotides
[no description available]		5.81170
oligonucleotide 5320
oligonucleotide 5320: a phosphorothioate oligonucleotide		3.110
raltegravir potassium
Raltegravir Potassium: A pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION.		2.0510
deoxyguanosine
[no description available]		1.9910purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
guanosine
ribonucleoside : Any nucleoside where the sugar component is D-ribose.		1.9910guanosines;
purines D-ribonucleoside		fundamental metabolite
thrombin aptamer
thrombin aptamer: nucleotide sequence given in first source; a synthetic polynucleotide		1.9910
ConditionIndicatedRelationship StrengthStudiesTrials
HIV Coinfection
[description not available]		03.8440
HIV Infections
Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).		03.8440
Acquired Immune Deficiency Syndrome
[description not available]		02.9110
Acquired Immunodeficiency Syndrome
An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.		02.9110
HIV
Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.		02.9110