Compounds > sungsanpin
Page last updated: 2024-11-13

sungsanpin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

sungsanpin: from a deep-sea streptomycete; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID71713252
CHEMBL ID2381503
MeSH IDM0587067

Synonyms (2)

Synonym
CHEMBL2381503
sungsanpin

Research Excerpts

Overview

Sungsanpin is a naturally derived lasso peptide that inhibits A549 cell invasion.

ExcerptReferenceRelevance
"Sungsanpin is a naturally derived lasso peptide that inhibits A549 cell invasion."( Rational Optimizations of the Marine-Derived Peptide Sungsanpin as Novel Inhibitors of Cell Invasion.
Chai, X; Chen, S; Gai, C; Li, A; Li, X; Zhao, Q; Zhuo, X; Zou, J; Zou, Y, 2023)		1.88
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (8)

Assay IDTitleYearJournalArticle
AID748058Cytotoxicity against human A549 cells up to 50 uM after 24 hrs by CCK-8 assay2013Journal of natural products, May-24, Volume: 76, Issue:5
Sungsanpin, a lasso peptide from a deep-sea streptomycete.
AID748054Antiinvasive activity against human A549 cells assessed as increase in TIMP-2 mRNA level after 24 hrs by RT-PCR analysis2013Journal of natural products, May-24, Volume: 76, Issue:5
Sungsanpin, a lasso peptide from a deep-sea streptomycete.
AID748057Antiinvasive activity against human A549 cells at 5 uM after 24 hrs by micro plate reader analysis relative to control2013Journal of natural products, May-24, Volume: 76, Issue:5
Sungsanpin, a lasso peptide from a deep-sea streptomycete.
AID748053Antiinvasive activity against human A549 cells assessed as MMP-2 mRNA level after 24 hrs by RT-PCR analysis2013Journal of natural products, May-24, Volume: 76, Issue:5
Sungsanpin, a lasso peptide from a deep-sea streptomycete.
AID748056Antiinvasive activity against human A549 cells at 50 uM after 24 hrs by micro plate reader analysis relative to control2013Journal of natural products, May-24, Volume: 76, Issue:5
Sungsanpin, a lasso peptide from a deep-sea streptomycete.
AID748055Antiinvasive activity against human A549 cells assessed as increase in TIMP-1 mRNA level after 24 hrs by RT-PCR analysis2013Journal of natural products, May-24, Volume: 76, Issue:5
Sungsanpin, a lasso peptide from a deep-sea streptomycete.
AID748052Antiinvasive activity against human A549 cells assessed as MMP-9 mRNA level after 24 hrs by RT-PCR analysis2013Journal of natural products, May-24, Volume: 76, Issue:5
Sungsanpin, a lasso peptide from a deep-sea streptomycete.
AID1612274Antiinvasive activity against human A549 cells assessed as inhibition of cell invasion at 50 uM after 24 hrs by crystal violet staining based transwell assay relative to control2018Journal of natural products, 10-26, Volume: 81, Issue:10
Ulleungdin, a Lasso Peptide with Cancer Cell Migration Inhibitory Activity Discovered by the Genome Mining Approach.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.80

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.80 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.59 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.80)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
ConditionIndicatedRelationship StrengthStudiesTrials
Cancer of Lung
[description not available]		02.5820
Lung Neoplasms
Tumors or cancer of the LUNG.		02.5820
Benign Neoplasms
[description not available]		02.1710
Invasiveness, Neoplasm
[description not available]		02.1710
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.		02.1710