Page last updated: 2024-11-13
sungsanpin
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
sungsanpin: from a deep-sea streptomycete; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 71713252 |
| CHEMBL ID | 2381503 |
| MeSH ID | M0587067 |
Synonyms (2)
| Synonym |
|---|
| CHEMBL2381503 |
| sungsanpin |
Research Excerpts
Overview
Sungsanpin is a naturally derived lasso peptide that inhibits A549 cell invasion.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Sungsanpin is a naturally derived lasso peptide that inhibits A549 cell invasion." | ( Rational Optimizations of the Marine-Derived Peptide Sungsanpin as Novel Inhibitors of Cell Invasion. Chai, X; Chen, S; Gai, C; Li, A; Li, X; Zhao, Q; Zhuo, X; Zou, J; Zou, Y, 2023) | 1.88 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (8)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID748058 | Cytotoxicity against human A549 cells up to 50 uM after 24 hrs by CCK-8 assay | 2013 | Journal of natural products, May-24, Volume: 76, Issue:5 | Sungsanpin, a lasso peptide from a deep-sea streptomycete. |
| AID748054 | Antiinvasive activity against human A549 cells assessed as increase in TIMP-2 mRNA level after 24 hrs by RT-PCR analysis | 2013 | Journal of natural products, May-24, Volume: 76, Issue:5 | Sungsanpin, a lasso peptide from a deep-sea streptomycete. |
| AID748057 | Antiinvasive activity against human A549 cells at 5 uM after 24 hrs by micro plate reader analysis relative to control | 2013 | Journal of natural products, May-24, Volume: 76, Issue:5 | Sungsanpin, a lasso peptide from a deep-sea streptomycete. |
| AID748053 | Antiinvasive activity against human A549 cells assessed as MMP-2 mRNA level after 24 hrs by RT-PCR analysis | 2013 | Journal of natural products, May-24, Volume: 76, Issue:5 | Sungsanpin, a lasso peptide from a deep-sea streptomycete. |
| AID748056 | Antiinvasive activity against human A549 cells at 50 uM after 24 hrs by micro plate reader analysis relative to control | 2013 | Journal of natural products, May-24, Volume: 76, Issue:5 | Sungsanpin, a lasso peptide from a deep-sea streptomycete. |
| AID748055 | Antiinvasive activity against human A549 cells assessed as increase in TIMP-1 mRNA level after 24 hrs by RT-PCR analysis | 2013 | Journal of natural products, May-24, Volume: 76, Issue:5 | Sungsanpin, a lasso peptide from a deep-sea streptomycete. |
| AID748052 | Antiinvasive activity against human A549 cells assessed as MMP-9 mRNA level after 24 hrs by RT-PCR analysis | 2013 | Journal of natural products, May-24, Volume: 76, Issue:5 | Sungsanpin, a lasso peptide from a deep-sea streptomycete. |
| AID1612274 | Antiinvasive activity against human A549 cells assessed as inhibition of cell invasion at 50 uM after 24 hrs by crystal violet staining based transwell assay relative to control | 2018 | Journal of natural products, 10-26, Volume: 81, Issue:10 | Ulleungdin, a Lasso Peptide with Cancer Cell Migration Inhibitory Activity Discovered by the Genome Mining Approach. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.80
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.80) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||