Compounds > succinimidyl 4-(4-maleimidophenyl)butyrate
Page last updated: 2024-11-07

succinimidyl 4-(4-maleimidophenyl)butyrate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

succinimidyl 4-(4-maleimidophenyl)butyrate: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID100681
SCHEMBL ID43979
MeSH IDM0125280

Synonyms (37)

Synonym
nsc344484
nsc-344484
79886-55-8
smpb
(2,5-dioxopyrrolidin-1-yl) 4-[4-(2,5-dioxopyrrol-1-yl)phenyl]butanoate
A9933
2,5-dioxopyrrolidin-1-yl 4-(4-(2,5-dioxo-2,5-dihydro-1h-pyrrol-1-yl)phenyl)butanoate
n-succinimidyl 4-(4-maleimidophenyl)butyrate
n-succinimidyl 4-(p-maleimidophenyl)butyrate
1h-pyrrole-2,5-dione, 1-(4-(4-((2,5-dioxo-1-pyrrolidinyl)oxy)-4-oxobutyl)phenyl)-
ps50 cpd
nsc 344484
succinimidyl 4-(4-maleimidophenyl)butyrate
4-(p-maleimidophenyl)butyric acid n-hydroxysuccinimide ester
4-(4-maleimidophenyl)butyric acid n-succinimidyl ester
4-(4-maleimidophenyl)butyric acid nhs ester
4-(4-maleimidophenyl)butyric acid n-hydroxysuccinimide ester
FT-0604065
SCHEMBL43979
succinimidyl 4-(p-maleimidophenyl)butyrate
4-n-maleimidophenyl butanoic acid-nhs
AKOS025312396
AS-74026
2,5-dioxopyrrolidin-1-yl 4-[4-(2,5-dioxo-2,5-dihydro-1h-pyrrol-1-yl)phenyl]butanoate
mfcd00054961
n-succinimidyl 4-[4-maleimidophenyl]butyrate
smpb crosslinker
n-succinimidyl 4-(4-maleimidophenyl)butyrate, >/=97%
PMJWDPGOWBRILU-UHFFFAOYSA-N ,
D92274
DTXSID601000817
1-(4-{4-[(2,5-dioxopyrrolidin-1-yl)oxy]-4-oxobutyl}phenyl)-1h-pyrrole-2,5-dione
smpb cross-linker
smpb cross linker
2,5-dioxopyrrolidin-1-yl4-(4-(2,5-dioxo-2,5-dihydro-1h-pyrrol-1-yl)phenyl)butanoate
benzenebutanoic acid, 4-(2,5-dihydro-2,5-dioxo-1h-pyrrol-1-yl)-, 2,5-dioxo-1-pyrrolidinyl ester
DLJ3SK2R6V
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (20.00)18.7374
1990's5 (50.00)18.2507
2000's3 (30.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.15

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.15 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.55 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.15)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
ammonium hydroxide
azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.		2.0310azane;
gas molecular entity;
mononuclear parent hydride		EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant
glutaric acid
glutaric acid: RN given refers to parent cpd. glutaric acid : An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid.		2.0310alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		Daphnia magna metabolite;
human metabolite
dihydroxyphenylalanine
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.. dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.		1.9810hydroxyphenylalanine;
non-proteinogenic alpha-amino acid;
tyrosine derivative		human metabolite
glutaric anhydride
glutaric anhydride: RN given in first source. glutaric anhydride : A cyclic dicarboxylic anhydride that is oxane which carries oxo groups at positions 2 and 6. It is used as an intermediate in the production of pharmaceuticals, corrosion inhibitors, and polymers (E.g. epoxy polyesters).		2.0310cyclic dicarboxylic anhydride;
oxanes
dodecylmercaptan
dodecylmercaptan: used in polymerization of neoprenes; structure		1.9610
hydrazine
diamine : Any polyamine that contains two amino groups.		1.9910azane;
hydrazines		EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
dithiothreitol
1,4-dimercaptobutane-2,3-diol : A glycol that is butane-2,3-diol in which a hydrogen from each of the methyl groups is replaced by a thiol group.. 1,4-dithiothreitol : The threo-diastereomer of 1,4-dimercaptobutane-2,3-diol.		1.96101,4-dimercaptobutane-2,3-diol;
butanediols;
dithiol;
glycol;
thiol		chelator;
human metabolite;
reducing agent
reactive orange
[no description available]		1.9910
n-succinimidyl 3-(2-pyridyldithio)propionate
N-succinimidyl 3-(2-pyridyldithio)propionate: heterobifunctional reagent		1.9610
n-hydroxysuccinimide s-acetylthioacetate
N-hydroxysuccinimide S-acetylthioacetate: introduces sulfhydryl groups into proteins; structure given in first source		1.9810
2-mercaptoacetate
2-mercaptoacetate: RN given refers to parent cpd		1.9810monocarboxylic acid anion
folic acid
folcysteine: used to promote fertility in chickens. vitamin B9 : Any B-vitamin that exhibits biological activity against vitamin B9 deficiency. Vitamin B9 refers to the many forms of folic acid and its derivatives, including tetrahydrofolic acid (the active form), methyltetrahydrofolate (the primary form found in blood), methenyltetrahydrofolate, folinic acid amongst others. They are present in abundance in green leafy vegetables, citrus fruits, and animal products. Lack of vitamin B9 leads to anemia, a condition in which the body cannot produce sufficient number of red blood cells. Symptoms of vitamin B9 deficiency include fatigue, muscle weakness, and pale skin.		1.9910folic acids;
N-acyl-amino acid		human metabolite;
mouse metabolite;
nutrient
ConditionIndicatedRelationship StrengthStudiesTrials
Cell Transformation, Viral
An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus.		01.9610
Adenocarcinoma, Basal Cell
[description not available]		01.9810
Cancer of Colon
[description not available]		01.9810
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.		01.9810
Adenocarcinoma
A malignant epithelial tumor with a glandular organization.		01.9810
Colonic Neoplasms
Tumors or cancer of the COLON.		01.9810