Page last updated: 2024-12-06

stearoyl-2-lactylic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Stearoyl-2-lactylic acid is a synthetic fatty acid ester that is a key component of several commercially available skincare products. It is typically produced through the esterification of stearic acid with lactic acid. This compound acts as an emollient, providing moisture and enhancing skin smoothness. It can also function as a surfactant, aiding in the absorption of other ingredients. Studies have shown that stearoyl-2-lactylic acid can improve skin hydration and reduce the appearance of fine lines and wrinkles. It is also thought to have potential antioxidant properties. The widespread use of stearoyl-2-lactylic acid in cosmetics stems from its ability to improve skin texture and appearance. Researchers continue to investigate its efficacy and potential benefits in skincare formulations.'

stearoyl-2-lactylic acid: RN given refers to Ca salt [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID22038
SCHEMBL ID451195
MeSH IDM0099084

Synonyms (23)

Synonym
14440-80-3
stearoyl-2-lactylic acid
brn 2164961
2-(1-carboxyethoxy)-1-methyl-2-oxoethyl stearate
octadecanoic acid, 2-(1-carboxyethoxy)-1-methyl-2-oxoethyl ester
stearoyllactoyllactic acid
marvic acid
stearic acid, ester with lactic acid bimol ester
einecs 238-418-2
stearoyl lactylic acid
stearolac
stearoyl-2-lactylate
2-(2-octadecanoyloxypropanoyloxy)propanoic acid
l98n90x0ni ,
stearoyl lactylate
unii-l98n90x0ni
SCHEMBL451195
stearic acid, ester with lactic acid bimol. ester
lactic acid, bimol. ester, stearate
stearyl lactylate
DTXSID1047231
Q27282867
2-((2-(stearoyloxy)propanoyl)oxy)propanoic acid

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" The no observed adverse effect level (NOAEL) of SSL was placed at 5%, the highest dietary level tested (equivalent to 2214 mg/kg/day for males and 2641 mg/kg/day for females)."( A one-year oral toxicity study of sodium stearoyl lactylate (SSL) in rats.
Hentz, K; Jonker, D; Junker, K; Lamb, J; Schmitt, D; Tran, N, 2010
)
0.36

Dosage Studied

ExcerptRelevanceReference
" For this reason, a dose response study was made to determine the optimal dietary dosage of LauL."( Efficacy of a lactylate on production performance and intestinal health of broilers during a subclinical Clostridium perfringens infection.
Cazemier, A; Else, AJ; Fabri, T; Lensing, M; van der Klis, JD, 2010
)
0.36
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (24)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (4.17)18.7374
1990's0 (0.00)18.2507
2000's3 (12.50)29.6817
2010's19 (79.17)24.3611
2020's1 (4.17)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.67

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.67 (24.57)
Research Supply Index3.22 (2.92)
Research Growth Index4.89 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.67)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (4.17%)6.00%
Case Studies1 (4.17%)4.05%
Observational0 (0.00%)0.25%
Other22 (91.67%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]