Page last updated: 2024-12-06

spizofurone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID71755
CHEMBL ID18098
CHEBI ID134864
SCHEMBL ID933718
MeSH IDM0133255

Synonyms (37)

Synonym
5-acetylspiro(benzofuran-2(3h),1'-cyclopropan)-3-one
spizofurone [inn:jan]
spizofuronum [latin]
spiro(benzofuran-2(3h),1'-cyclopropan)-3-one, 5-acetyl-
ccris 1922
brn 5334898
espizofurona [spanish]
maon
spizofurone
ag-629
CHEBI:134864
72492-12-7
CHEMBL18098
5-acetylspiro[1-benzofuran-2,1'-cyclopropane]-3-one
5-acetylspiro[benzofuran-2(3h),1'-cyclopropan]-3-one
A837543
A9590
spizofuronum
espizofurona
94f21t5g3c ,
unii-94f21t5g3c
FT-0630810
AKOS015915227
spizofurone [jan]
spizofurone [who-dd]
spizofurone [inn]
spizofurone [mi]
SETMGIIITGNLAS-UHFFFAOYSA-N
5-acetylspiro[benzo[b]furan-2(3h), 1'-cyclopropane]-3-one
5-acetylspiro[benzo-[b]furan-2(3h), 1'-cyclopropane]-3-one
5-acetylspiro[benzo[b]furan-2(3h),1'-cyclopropane]-3-one
SCHEMBL933718
5-acetyl-3h-spiro[benzofuran-2,1'-cyclopropan]-3-one
sr-01000944986
SR-01000944986-1
Q27271678
DTXSID20868144
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
benzofurans
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (7)

Assay IDTitleYearJournalArticle
AID184305Compound was evaluated for the duration of cytoprotective effect, in Ethanol-Necrosis model, that causes inhibition of ulceration. Absolute ethanol was administered at 8 hr after dosing1992Journal of medicinal chemistry, Apr-03, Volume: 35, Issue:7
Synthesis and antiulcer activity of novel 5-(2-ethenyl substituted)-3(2H)-furanones.
AID177424Effective dose that inhibits formation of induced gastric lesions.1992Journal of medicinal chemistry, Apr-03, Volume: 35, Issue:7
Synthesis and antiulcer activity of novel 5-(2-ethenyl substituted)-3(2H)-furanones.
AID183905Inhibitory activity In the indomethacin model.1992Journal of medicinal chemistry, Apr-03, Volume: 35, Issue:7
Synthesis and antiulcer activity of novel 5-(2-ethenyl substituted)-3(2H)-furanones.
AID178996Inhibitory activity against ethanol-induced lesions, which was administered after 1 hr of oral dosing in pylorus-ligated rat model.1992Journal of medicinal chemistry, Apr-03, Volume: 35, Issue:7
Synthesis and antiulcer activity of novel 5-(2-ethenyl substituted)-3(2H)-furanones.
AID184304Compound was evaluated for the duration of cytoprotective effect, in Ethanol-Necrosis model, that causes inhibition of ulceration. Absolute ethanol was administered at 6 hr after dosing1992Journal of medicinal chemistry, Apr-03, Volume: 35, Issue:7
Synthesis and antiulcer activity of novel 5-(2-ethenyl substituted)-3(2H)-furanones.
AID183900Inhibitory activity In acidified aspirin model1992Journal of medicinal chemistry, Apr-03, Volume: 35, Issue:7
Synthesis and antiulcer activity of novel 5-(2-ethenyl substituted)-3(2H)-furanones.
AID184301Evaluated for the duration of cytoprotective effect, in Ethanol-Necrosis model, that causes inhibition of ulceration. Absolute ethanol was administered at 4 hr after dosing1992Journal of medicinal chemistry, Apr-03, Volume: 35, Issue:7
Synthesis and antiulcer activity of novel 5-(2-ethenyl substituted)-3(2H)-furanones.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (66.67)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.41

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.41 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.36 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.41)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]