Page last updated: 2024-12-06

spirobromin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

spirobromin: RN refers to dichloride compound [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID72114
CHEMBL ID2106677
SCHEMBL ID18399
MeSH IDM0154738

Synonyms (29)

Synonym
spirobromin
dibrospidium chloride [inn]
3,12-bis(3-bromopropionyl)-3,12-diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane dichloride
spirobromine
chlorure de dibrospidium [french]
n,n(sup 3)-di(beta-bromopropionyl)-n(sup 1),n(sup 2)-dispirotripiperazinium dichloride
cloruro de dibrospidio [spanish]
3,12-bis(3-bromo-1-oxopropyl)-3,12-diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane dichloride
dibrospidium chloride
dibrospidii chloridum [latin]
n,n'''-di(beta-bromopropionyl)-n',n''-dispirotripiperazinium dichloride
3,12-diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane, 3,12-bis(3-bromo-1-oxopropyl)-, dichloride
86641-76-1
AKOS005267224
3,12-bis(3-bromopropanoyl)-3,12-diaza-6,9-diazoniadispiro[5.2.5.2]hexadecane dichloride
cloruro de dibrospidio
chlorure de dibrospidium
grx5l9y3z3 ,
unii-grx5l9y3z3
dibrospidii chloridum
FT-0683008
CHEMBL2106677
SCHEMBL18399
Q16644083
3,12-bis(3-bromopropanoyl)-3,6,9,12-tetraazadispiro[5.2.5~9~.2~6~]hexadecane-6,9-diium dichloride
DTXSID101006989
3-bromo-1-[12-(3-bromopropanoyl)-3,12-diaza-6,9-diazoniadispiro[5.2.59.26]hexadecan-3-yl]propan-1-one;dichloride
3,12-bis(3-bromopropanoyl)-3,6,9,12-tetraazadispiro[5.2.5(9).2(6)]hexadecane-6,9-diium chloride
CS-0456652
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID1915658Antiviral activity against HSV-1 assessed as viral growth inhibition2021European journal of medicinal chemistry, Feb-05, Volume: 211Dispirotripiperazine-core compounds, their biological activity with a focus on broad antiviral property, and perspectives in drug design (mini-review).
AID1915660Toxicity in herpetic encephalitis mouse model assessed as reduction in mortality at 250 mg/kg,po bid for 5 days2021European journal of medicinal chemistry, Feb-05, Volume: 211Dispirotripiperazine-core compounds, their biological activity with a focus on broad antiviral property, and perspectives in drug design (mini-review).
AID1915659Toxicity in mouse assessed as lethal dose at ip as single dose2021European journal of medicinal chemistry, Feb-05, Volume: 211Dispirotripiperazine-core compounds, their biological activity with a focus on broad antiviral property, and perspectives in drug design (mini-review).
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (9.09%)6.00%
Case Studies1 (9.09%)4.05%
Observational0 (0.00%)0.25%
Other9 (81.82%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]