Compounds > sj 172550
Page last updated: 2024-11-09

sj 172550

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

SJ 172550: has antineoplastic activity; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID1317464
CHEMBL ID4303491
SCHEMBL ID22092449
SCHEMBL ID22092451
MeSH IDM0546468

Synonyms (21)

Synonym
methyl {2-chloro-6-ethoxy-4-[(e)-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4h-pyrazol-4-ylidene)methyl]phenoxy}acetate
STK165480
AKOS000330842
methyl 2-[2-chloro-6-ethoxy-4-[(e)-(3-methyl-5-oxo-1-phenylpyrazol-4-ylidene)methyl]phenoxy]acetate
sj-172550
2-[2-chloro-4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4h-pyrazol-4-ylidene)methyl]-6-ethoxyphenoxy]-acetic acid methyl ester
CS-3177
HY-16664
MLS006011707
smr004703434
sj 172550
E76862
cid 1317464
methyl 2-(2-chloro-6-ethoxy-4-((3-methyl-5-oxo-1-phenyl-1h-pyrazol-4(5h)-ylidene)methyl)phenoxy)acetate
CHEMBL4303491
A913674
BS-51438
SCHEMBL22092449
SCHEMBL22092451
methyl2-(2-chloro-6-ethoxy-4-((3-methyl-5-oxo-1-phenyl-1h-pyrazol-4(5h)-ylidene)methyl)phenoxy)acetate
AKOS040742634
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID1347411qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Mechanism Interrogation Plate v5.0 (MIPE) Libary2020ACS chemical biology, 07-17, Volume: 15, Issue:7
High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (85.71)24.3611
2020's1 (14.29)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 18.43

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index18.43 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index5.33 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (18.43)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
methyl acetate
methyl acetate : An acetate ester resulting from the formal condensation of acetic acid with methanol. A low-boiling (57 degreeC) colourless, flammable liquid, it is used as a solvent for many resins and oils.		2.0810acetate ester;
methyl ester;
volatile organic compound		EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor;
fragrance;
polar aprotic solvent
phenyl acetate
phenyl acetate: The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.. phenyl acetate : An acetate ester obtained by the formal condensation of phenol with acetic acid.		3.3460benzenes;
phenyl acetates
carbocyanines
Carbocyanines: Compounds that contain three methine groups. They are frequently used as cationic dyes used for differential staining of biological materials.		2.1710cyanine dye;
organic iodide salt		fluorochrome
nutlin-3a
nutlin 3: an MDM2 antagonist; structure in first source		2.1110stilbenoid
ConditionIndicatedRelationship StrengthStudiesTrials
Eye Cancer, Retinoblastoma
[description not available]		02.0510
Retinoblastoma
A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)		02.0510