seryl-isoleucyl-lysyl-valyl-alanyl-valinamide profile

seryl-isoleucyl-lysyl-valyl-alanyl-valinamide: laminin-derived SIKVAV-containing peptide can promote angiogenesis & tumor growth [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	5487517
SCHEMBL ID	2191316
MeSH ID	M0208254

Synonym
seryl-isoleucyl-lysyl-valyl-alanyl-valinamide
146163-06-6
l-valinamide, l-seryl-l-isoleucyl-l-lysyl-l-valyl-l-alanyl-
sikvav
(2s)-6-amino-2-[[(2s,3s)-2-[[(2s)-2-amino-3-hydroxypropanoyl]amino]-3-methylpentanoyl]amino]-n-[(2s)-1-[[(2s)-1-[[(2s)-1-amino-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]hexanamide
SCHEMBL2191316
DTXSID30163278

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	3 (17.65)	18.2507
2000's	9 (52.94)	29.6817
2010's	5 (29.41)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	2 (11.76%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	15 (88.24%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
pd 98059 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source. 2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.	2.03	1	aromatic amine; monomethoxyflavone	EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; geroprotector
hydroxymethylmethacrylate [no description available]	2.13	1
arginyl-glycyl-aspartic acid arginyl-glycyl-aspartic acid: amino acid sequence of basic unit of widespread cellular recognition system	3.54	2	oligopeptide
arginyl-glycyl-aspartyl-serine arginyl-glycyl-aspartyl-serine: corresponds to cell attachment site of fibronectin; located near carboxyl-terminal region of alpha-chain of fibrinogen; inhibits platelet aggregation & fibrinogen binding to activated platelets	2.13	1
glycyl-arginyl-glycyl-aspartyl-serine glycyl-arginyl-glycyl-aspartyl-serine: synthetic peptide from fibronectins; inhibits experimental metastasis of murine melanoma cells	1.99	1
tyrosyl-isoleucyl-glycyl-seryl-arginine tyrosyl-isoleucyl-glycyl-seryl-arginine: a synthetic laminin pentapeptide	3.11	1
neuropeptide y Neuropeptide Y: A 36-amino acid peptide present in many organs and in many sympathetic noradrenergic neurons. It has vasoconstrictor and natriuretic activity and regulates local blood flow, glandular secretion, and smooth muscle activity. The peptide also stimulates feeding and drinking behavior and influences secretion of pituitary hormones.	3.1	1
tigapotide tigapotide: a synthetic peptide corresponding to amino acids 31-45 of PSP94 (prostate secretory protein) that inhibits matrix metalloproteinase-9 secretion	2.03	1
chitosan [no description available]	2.17	1

Condition	Relationship Strength	Studies
Injuries, Spinal Cord [description not available]	2.54	2
Spinal Cord Injuries Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).	2.54	2
Adenocystic Carcinoma [description not available]	2.71	3
Cancer of Salivary Gland [description not available]	2.93	4
Carcinoma, Adenoid Cystic Carcinoma characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells. When the cylinders occur within masses of epithelial cells, they give the tissue a perforated, sievelike, or cribriform appearance. Such tumors occur in the mammary glands, the mucous glands of the upper and lower respiratory tract, and the salivary glands. They are malignant but slow-growing, and tend to spread locally via the nerves. (Dorland, 27th ed)	2.71	3
Salivary Gland Neoplasms Tumors or cancer of the SALIVARY GLANDS.	2.93	4
Metastase [description not available]	2.92	1
Benign Neoplasms [description not available]	2.92	1
Neoplastic Processes The pathological mechanisms and forms taken by tissue during degeneration into a neoplasm and its subsequent activity.	2.92	1
Angiogenesis, Pathologic [description not available]	4.07	3
Blood Clot [description not available]	2.92	1
Invasiveness, Neoplasm [description not available]	2.92	1
Neoplasm Metastasis The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.	2.92	1
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	2.92	1
Thrombosis Formation and development of a thrombus or blood clot in the blood vessel.	2.92	1
Myoepithelial Tumor [description not available]	2.02	1
Myoepithelioma A usually benign tumor made up predominantly of myoepithelial cells.	2.02	1
B16 Melanoma [description not available]	2.4	2
Bone Cancer [description not available]	2.03	1
Cancer of Prostate [description not available]	2.44	2
Bone Neoplasms Tumors or cancer located in bone tissue or specific BONES.	2.03	1
Prostatic Neoplasms Tumors or cancer of the PROSTATE.	2.44	2
Ischemia A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.	2.92	1
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	1.98	1

seryl-isoleucyl-lysyl-valyl-alanyl-valinamide

Description

Cross-References

Synonyms (7)

Research

Studies (17)

Market Indicators

Research Demand Index: 11.69

Study Types