scopularide A: found in the fungus Scopulariopsis brevicaulis, which was isolated from the marine sponge Tethya aurantium; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 24899412 |
| CHEMBL ID | 507120 |
| MeSH ID | M0524643 |
| Synonym |
|---|
| CHEMBL507120 |
| scopularide a |
Scopularide A is a promising potent anticancer lipopeptide isolated from a marine derived Scopulariopsis brevicaulis strain.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Scopularide A is a promising potent anticancer lipopeptide isolated from a marine derived Scopulariopsis brevicaulis strain. " | ( Identification of the Scopularide Biosynthetic Gene Cluster in Scopulariopsis brevicaulis. Kempken, F; Kumar, A; Lukassen, MB; Saei, W; Sondergaard, TE; Sørensen, JL; Tamminen, A; Wiebe, MG, 2015) | 1.86 |
| Excerpt | Reference | Relevance |
|---|---|---|
| "Scopularide A production has been transferred from a non-agitated to a stirred tank bioreactor environment with an approximately 6-fold increase in specific and 29-fold increase in volumetric production. " | ( Production of scopularide A in submerged culture with Scopulariopsis brevicaulis. Kramer, A; Labes, A; Tamminen, A; Wiebe, MG, 2014) | 2.21 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID405484 | Antitumor activity against human HT29 cells assessed as reduction of viability at 10 ug/ml | 2008 | Journal of natural products, Jun, Volume: 71, Issue:6 | Scopularides A and B, cyclodepsipeptides from a marine sponge-derived fungus, Scopulariopsis brevicaulis. |
| AID407494 | Antimicrobial activity against Escherichia coli | 2008 | Journal of natural products, Jun, Volume: 71, Issue:6 | Scopularides A and B, cyclodepsipeptides from a marine sponge-derived fungus, Scopulariopsis brevicaulis. |
| AID407497 | Antitumor activity against human Colo357 cells assessed as reduction of viability at 10 ug/ml | 2008 | Journal of natural products, Jun, Volume: 71, Issue:6 | Scopularides A and B, cyclodepsipeptides from a marine sponge-derived fungus, Scopulariopsis brevicaulis. |
| AID407495 | Antimicrobial activity against Pseudomonas fluorescens | 2008 | Journal of natural products, Jun, Volume: 71, Issue:6 | Scopularides A and B, cyclodepsipeptides from a marine sponge-derived fungus, Scopulariopsis brevicaulis. |
| AID407496 | Antimicrobial activity against Candida glabrata | 2008 | Journal of natural products, Jun, Volume: 71, Issue:6 | Scopularides A and B, cyclodepsipeptides from a marine sponge-derived fungus, Scopulariopsis brevicaulis. |
| AID405483 | Antitumor activity against human Panc89 cells assessed as reduction of viability at 10 ug/ml | 2008 | Journal of natural products, Jun, Volume: 71, Issue:6 | Scopularides A and B, cyclodepsipeptides from a marine sponge-derived fungus, Scopulariopsis brevicaulis. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (13.25) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||