Compounds > sclerotigenin
Page last updated: 2024-11-12

sclerotigenin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

sclerotigenin: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID10802469
CHEMBL ID490538
SCHEMBL ID10871850
MeSH IDM0533643

Synonyms (10)

Synonym
inchi=1/c16h11n3o2/c20-15-11-6-2-4-8-13(11)19-14(9-17-15)18-12-7-3-1-5-10(12)16(19)21/h1-8h,9h2,(h,17,20)
ngykottxjaplpc-uhfffaoysa-
sclerotigenin
CHEMBL490538
SCHEMBL10871850
NGYKOTTXJAPLPC-UHFFFAOYSA-N
6,7-dihydro-5h,13h-quinazolino[3,2-a][1,4]benzodiazepine-5,13-dione
65641-84-1
6,7-dihydro-quinazolino[3,2-a][1,4]benzodiazepine-5,13-dione
6,7-dihydroquinazolino[3,2-a][1,4]benzodiazepine-5,13-dione
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (11)

Assay IDTitleYearJournalArticle
AID1525117Antibacterial activity against Staphylococcus aureus2019Journal of natural products, 05-24, Volume: 82, Issue:5
Raistrickindole A, an Anti-HCV Oxazinoindole Alkaloid from Penicillium raistrickii IMB17-034.
AID1525119Antibacterial activity against Escherichia coli2019Journal of natural products, 05-24, Volume: 82, Issue:5
Raistrickindole A, an Anti-HCV Oxazinoindole Alkaloid from Penicillium raistrickii IMB17-034.
AID1525118Antibacterial activity against Enterococcus faecalis2019Journal of natural products, 05-24, Volume: 82, Issue:5
Raistrickindole A, an Anti-HCV Oxazinoindole Alkaloid from Penicillium raistrickii IMB17-034.
AID1525123Selectivity index, ratio of CC50 for Cytotoxicity against human Huh7.5 cells to EC50 for antiviral activity against HCV infected in human Huh7.5 cells2019Journal of natural products, 05-24, Volume: 82, Issue:5
Raistrickindole A, an Anti-HCV Oxazinoindole Alkaloid from Penicillium raistrickii IMB17-034.
AID1525120Antibacterial activity against Pseudomonas aeruginosa2019Journal of natural products, 05-24, Volume: 82, Issue:5
Raistrickindole A, an Anti-HCV Oxazinoindole Alkaloid from Penicillium raistrickii IMB17-034.
AID1525114Cytotoxicity against human A549 cells2019Journal of natural products, 05-24, Volume: 82, Issue:5
Raistrickindole A, an Anti-HCV Oxazinoindole Alkaloid from Penicillium raistrickii IMB17-034.
AID1525115Cytotoxicity against human NCI-H460 cells2019Journal of natural products, 05-24, Volume: 82, Issue:5
Raistrickindole A, an Anti-HCV Oxazinoindole Alkaloid from Penicillium raistrickii IMB17-034.
AID1525122Cytotoxicity against human Huh7.5 cells assessed as reduction in cell viability2019Journal of natural products, 05-24, Volume: 82, Issue:5
Raistrickindole A, an Anti-HCV Oxazinoindole Alkaloid from Penicillium raistrickii IMB17-034.
AID1525116Cytotoxicity against human HCT116 cells2019Journal of natural products, 05-24, Volume: 82, Issue:5
Raistrickindole A, an Anti-HCV Oxazinoindole Alkaloid from Penicillium raistrickii IMB17-034.
AID1525121Antiviral activity against HCV infected in human Huh7.5 cells assessed as reduction in intracellular HCV RNA incubated for 72 hrs by real-time one-step reverse-transcription polymerase chain reaction assay2019Journal of natural products, 05-24, Volume: 82, Issue:5
Raistrickindole A, an Anti-HCV Oxazinoindole Alkaloid from Penicillium raistrickii IMB17-034.
AID379485Insecticidal activity against first instar larvae of Helicoverpa zea at 200 ppm administered with diet relative to control1999Journal of natural products, Apr, Volume: 62, Issue:4
Sclerotigenin: A new antiinsectan benzodiazepine from the sclerotia of penicillium sclerotigenum
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (4)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.76

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.76 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.55 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.76)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
asperlicin c
asperlicin C: cholecystokinin antagonist; from Aspergillus alliaceus; structure given in first source; MF C25-H18-N4-O2. asperlicin C : A member of the class of asperlicins in which the core 6,7-dihydroquinazolino[3,2-a][1,4]benzodiazepine-5,13-dione skeleton is substituted at the 7 pro-S position by an indol-3-ylmethyl group. It is a cholecystokinin antagonist.		2.4620asperlicins;
indoles;
organic heterotetracyclic compound		Aspergillus metabolite;
cholecystokinin antagonist
telaprevir
[no description available]		2.2110cyclopentapyrrole;
cyclopropanes;
oligopeptide;
pyrazines		antiviral drug;
hepatitis C protease inhibitor;
peptidomimetic
tin
[no description available]		7.0510carbon group element atom;
elemental tin;
metal atom		micronutrient
circumdatin f
circumdatin F: from the fungus, Aspergillus ochraceus; structure in first source		2.4620
ConditionIndicatedRelationship StrengthStudiesTrials