Compounds > salpichrolide c
Page last updated: 2024-11-13

salpichrolide c

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

salpichrolide C: isolated from Salpichroa origanifolia; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
Salpichroagenus[no description available]SolanaceaeA plant family of the order SOLANALES, class MAGNOLIOPSIDA. Among the most noted are POTATOES; TOMATOES; CAPSICUM (green and red peppers); TOBACCO; and BELLADONNA.[MeSH]

Cross-References

ID SourceID
PubMed CID44558901
CHEMBL ID470235
MeSH IDM0422852

Synonyms (2)

Synonym
CHEMBL470235
salpichrolide c
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (10)

Assay IDTitleYearJournalArticle
AID480906Antiproliferative activity against estrogen receptor deficient human SKBR3 cells after 48 hrs by SRB assay2010Journal of natural products, May-28, Volume: 73, Issue:5
Antiproliferative activity of withanolides against human breast cancer cell lines.
AID376851Antifeedant activity against Musca domestica CIPEIN larvae assessed as inhibition of larvae development after 18 days2000Journal of natural products, Aug, Volume: 63, Issue:8
Antifeedant activity of withanolides from Salpichroa origanifolia on Musca domestica.
AID480904Antiproliferative activity against human MCF7/BUS cells expressing estrogen receptor after 48 hrs by SRB assay2010Journal of natural products, May-28, Volume: 73, Issue:5
Antiproliferative activity of withanolides against human breast cancer cell lines.
AID376597Antifeedant activity in Musca domestica CIPEIN larvae assessed as time needed to pupate 50% at 100 ppm2000Journal of natural products, Aug, Volume: 63, Issue:8
Antifeedant activity of withanolides from Salpichroa origanifolia on Musca domestica.
AID480905Antiproliferative activity against estrogen receptor deficient human MDA-MB-231 cells after 48 hrs by SRB assay2010Journal of natural products, May-28, Volume: 73, Issue:5
Antiproliferative activity of withanolides against human breast cancer cell lines.
AID376857Antifeedant activity against Musca domestica CIPEIN larvae assessed as larval mortality at 200 ppm after 18 days2000Journal of natural products, Aug, Volume: 63, Issue:8
Antifeedant activity of withanolides from Salpichroa origanifolia on Musca domestica.
AID376855Antifeedant activity against Musca domestica CIPEIN larvae assessed as time needed to pupate 50% at 500 ppm2000Journal of natural products, Aug, Volume: 63, Issue:8
Antifeedant activity of withanolides from Salpichroa origanifolia on Musca domestica.
AID376856Antifeedant activity against Musca domestica CIPEIN larvae assessed as time needed to pupate 50% at 2000 ppm2000Journal of natural products, Aug, Volume: 63, Issue:8
Antifeedant activity of withanolides from Salpichroa origanifolia on Musca domestica.
AID480902Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 48 hrs by SRB assay2010Journal of natural products, May-28, Volume: 73, Issue:5
Antiproliferative activity of withanolides against human breast cancer cell lines.
AID480903Antiproliferative activity against human T47D cells expressing estrogen receptor after 48 hrs by SRB assay2010Journal of natural products, May-28, Volume: 73, Issue:5
Antiproliferative activity of withanolides against human breast cancer cell lines.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.79

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.79 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.73 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.79)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
fluorouracil
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.. 5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.		2.0510nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
camptothecin
NSC 100880: carboxylate (opened lactone) form of camptothecin; RN refers to (S)-isomer; structure given in first source		2.0510delta-lactone;
pyranoindolizinoquinoline;
quinoline alkaloid;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
genotoxin;
plant metabolite
4beta-Hydroxywithanolide E
[no description available]		2.0510withanolide
withanolides
Withanolides: Ergostane derivatives of 28 carbons with oxygens at C1, C22, and C26 positions and the side chain cyclized. They are found in WITHANIA plant genus and have cytotoxic and other effects.		2.4520
ergosterol
[no description available]		2.96403beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols		fungal metabolite;
Saccharomyces cerevisiae metabolite
salpichrolide a
salpichrolide A: isolated from Salpichroa origanifolia; structure in first source		2.9640
salpichrolide g
salpichrolide G: withanolide from Salpichroa origanifolia; structure in first source		2.9340
ConditionIndicatedRelationship StrengthStudiesTrials
Breast Cancer
[description not available]		02.0510
Breast Neoplasms
Tumors or cancer of the human BREAST.		02.0510