salpichrolide a profile

salpichrolide A: isolated from Salpichroa origanifolia; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Related Flora

Flora	Rank	Flora Definition	Family	Family Definition
Salpichroa	genus	[no description available]	Solanaceae	A plant family of the order SOLANALES, class MAGNOLIOPSIDA. Among the most noted are POTATOES; TOMATOES; CAPSICUM (green and red peppers); TOBACCO; and BELLADONNA.[MeSH]

Cross-References

ID Source	ID
PubMed CID	6712055
MeSH ID	M0422869

Synonyms (5)

Synonym
NCI60_018821
salpichrolide a
nsc-654207
nsc654207
(2r)-15-[1-[(1s,2r,6s)-2-hydroxy-1,6-dimethyl-3,7-dioxabicyclo[4.1.0]heptan-4-yl]ethyl]-2-methyl-8-oxapentacyclo[9.8.0.02,7.07,9.012,17]nonadeca-4,12(17),13,15-tetraen-3-one

Research Excerpts

Dosage Studied

Excerpt	Relevance	Reference
" The antiestrogenic activity was evaluated by performing dose-response experiments in ER(+) MCF-7 breast cancer cells."	( Synthesis and biological evaluation of salpichrolide analogs as antiestrogenic agents. Alvarez, LD; Burton, G; Gargiulo, L; Lüthy, I; Rivero, EM; Sonego, JM; Veleiro, AS, 2014)	0.67

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (33.33)	29.6817
2010's	4 (66.67)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.79

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.79 (24.57)
Research Supply Index	1.95 (2.92)
Research Growth Index	4.73 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.79)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	6 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
withanolides Withanolides: Ergostane derivatives of 28 carbons with oxygens at C1, C22, and C26 positions and the side chain cyclized. They are found in WITHANIA plant genus and have cytotoxic and other effects.	2.45	2
ergosterol [no description available]	3.31	6	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; ergostanoid; phytosterols	fungal metabolite; Saccharomyces cerevisiae metabolite
salpichrolide c salpichrolide C: isolated from Salpichroa origanifolia; structure in first source	2.96	4
salpichrolide g salpichrolide G: withanolide from Salpichroa origanifolia; structure in first source	2.72	3

salpichrolide a

Description