| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
glycerol
Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil. | 2.02 | 1 | 0 | alditol;
triol | algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent |
thiazoles
[no description available] | 3.14 | 1 | 0 | 1,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene | |
palladium
Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46. | 2.06 | 1 | 0 | metal allergen;
nickel group element atom;
platinum group metal atom | |
ruthenium
Ruthenium: A hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44, and atomic weight 101.07. It is used as a catalyst and hardener for PLATINUM and PALLADIUM. | 2.01 | 1 | 0 | iron group element atom;
platinum group metal atom | |
rhamnose
[no description available] | 2.42 | 2 | 0 | L-rhamnose | |
alkenes
[no description available] | 3.53 | 2 | 0 | | |
niflumic acid
strictifolione: structure in first source | 3.21 | 1 | 0 | | |
orlistat
Orlistat: A lactone derivative of LEUCINE that acts as a pancreatic lipase inhibitor to limit the absorption of dietary fat; it is used in the management of obesity.. orlistat : A carboxylic ester resulting from the formal condensation of the carboxy group of N-formyl-L-leucine with the hydroxy group of (3S,4S)-3-hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one. A pancreatic lipase inhibitor, it is used as an anti-obesity drug. | 3.21 | 1 | 0 | beta-lactone;
carboxylic ester;
formamides;
L-leucine derivative | anti-obesity agent;
bacterial metabolite;
EC 2.3.1.85 (fatty acid synthase) inhibitor;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor |
bafilomycin a
[no description available] | 3.14 | 1 | 0 | | |
bafilomycin a1
bafilomycin A1: from Streptomyces griseus; structure given in first source. bafilomycin A1 : The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus. | 7.02 | 1 | 0 | cyclic hemiketal;
macrolide antibiotic;
oxanes | apoptosis inducer;
autophagy inhibitor;
bacterial metabolite;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor;
ferroptosis inhibitor;
fungicide;
potassium ionophore;
toxin |
concanamycin a
concanamycin A: from Streptomyces diastatochromogenes S-45; inhibits vacuolar H+ ATPase. concanamycin A : A concanamycin in which the lactone ring contains 4 double bonds and is substituted by 4 methyl groups, 2 hydroxy groups, 2 methoxy groups and an ethyl group. | 3.14 | 1 | 0 | carbamate ester;
concanamycin | antifungal agent;
EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor;
metabolite |
dolabelide c
dolabelide C: from sea hare, Dolabella auricularia (family Aplysiidae); structure in first source | 3.21 | 1 | 0 | | |
apicularen b
apicularen B: isolated from Chondromyces; structure in first source | 2 | 1 | 0 | | |
apicularen a
apicularen A: isolated from Chondromyces; structure in first source | 3.81 | 3 | 0 | | |
saliphenylhalamide
saliphenylhalamide: a V-ATPase inhibitor; structure in first source | 7.47 | 2 | 0 | | |
cruentaren a
cruentaren A: an antifungal agent isolated from Byssovorax cruenta; structure in first source | 3.14 | 1 | 0 | macrolide | |
archazolid a
archazolid A: inhibits vacuolar-type ATPase; isolated from Archangium gephyra; structure in first source | 3.14 | 1 | 0 | | |
salicylates
Salicylates: The salts or esters of salicylic acids, or salicylate esters of an organic acid. Some of these have analgesic, antipyretic, and anti-inflammatory activities by inhibiting prostaglandin synthesis.. hydroxybenzoate : Any benzoate derivative carrying a single carboxylate group and at least one hydroxy substituent.. salicylates : Any salt or ester arising from reaction of the carboxy group of salicylic acid, or any ester resulting from the condensation of the phenolic hydroxy group of salicylic acid with an organic acid.. salicylate : A monohydroxybenzoate that is the conjugate base of salicylic acid. | 4.04 | 4 | 0 | monohydroxybenzoate | plant metabolite |
oximidine iii
oximidine III: an antitumor antibiotic isolated from Pseudomonas; structure in first source | 2.02 | 1 | 0 | | |