| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
spermine
[no description available] | 1.98 | 1 | 0 | polyazaalkane;
tetramine | antioxidant;
fundamental metabolite;
immunosuppressive agent |
lomustine
[no description available] | 1.98 | 1 | 0 | N-nitrosoureas;
organochlorine compound | alkylating agent;
antineoplastic agent |
n(1),n(11)-diethylnorspermine
N(1),N(11)-diethylnorspermine: structure given in first source | 3.1 | 1 | 0 | | |
n(1), n(12)-diethylspermine
N(1), N(12)-diethylspermine: structure in first source. N(1),N(12)-diethylspermine : A substituted spermine that is spermine in which a hydrogen attached to each of the primary amino groups has been replaced by an ethyl group. | 3.1 | 1 | 0 | polyazaalkane;
secondary amino compound;
substituted spermine;
tetramine | antineoplastic agent |
melarsen oxide
melarsen oxide: inhibits glutathione reductase | 3.1 | 1 | 0 | | |
n(1),n(14)-bis(ethyl)homospermine
N(1),N(14)-bis(ethyl)homospermine: structure given in first source; depletes polyamines and inhibits the growth of tumor cells in tissue culture | 3.1 | 1 | 0 | | |
adenosine
quinquefolan B: isolated from roots of Panax quinquefolium L.; RN not in Chemline 10/87; RN from Toxlit | 2.89 | 4 | 0 | adenosines;
purines D-ribonucleoside | analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent |
mdl 27695
MDL 27695: structure given in first source | 3.1 | 1 | 0 | | |
n-butyl-1,3-diaminopropane
N-butyl-1,3-diaminopropane: RN given refers to parent cpd | 1.98 | 1 | 0 | | |
clomesone
clomesone: structure & RN given in first source | 1.98 | 1 | 0 | | |
s-adenosyl-3-thio-1,8-diaminooctane
S-adenosyl-3-thio-1,8-diaminooctane: structure given in first source | 3.49 | 2 | 0 | | |
n(1),n(8)-diethylspermidine
N(1),N(8)-diethylspermidine: regulator of ornithine decarboxylase | 3.1 | 1 | 0 | | |
5'-methylthioadenosine
5'-methylthioadenosine: structure. 5'-S-methyl-5'-thioadenosine : Adenosine with the hydroxy group at C-5' substituted with a methylthio (methylsulfanyl) group. | 1.97 | 1 | 0 | thioadenosine | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
mitoguazone
Mitoguazone: Antineoplastic agent effective against myelogenous leukemia in experimental animals. Also acts as an inhibitor of animal S-adenosylmethionine decarboxylase.. mitoguazone : A hydrazone obtained by formal condensation of the two carbonyl groups of methylglyoxal with the primary amino groups of two molecules of aminoguanidine. | 3.1 | 1 | 0 | guanidines;
hydrazone | antineoplastic agent;
apoptosis inducer;
EC 4.1.1.50 (adenosylmethionine decarboxylase) inhibitor |
s-adenosylmethionine
(R)-S-adenosyl-L-methionine : An S-adenosyl-L-methionine that has R-configuration.. S-adenosyl-L-methionine zwitterion : A zwitterionic tautomer of S-adenosyl-L-methionine arising from shift of the proton from the carboxy group to the amino group.. (R)-S-adenosyl-L-methionine zwitterion : An S-adenosyl-L-methionine zwitterion that has R-configuration; major species at pH 7.3.. (S)-S-adenosyl-L-methionine zwitterion : An S-adenosyl-L-methionine zwitterion that has S-configuration; major species at pH 7.3.. S-adenosyl-L-methionine : A sulfonium compound that is the S-adenosyl derivative of L-methionine. It is an intermediate in the metabolic pathway of methionine. | 1.97 | 1 | 0 | organic cation;
sulfonium compound | coenzyme;
cofactor;
human metabolite;
micronutrient;
Mycoplasma genitalium metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite |