Page last updated: 2024-12-07

s-(n-methylcarbamoyl)glutathione

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

S-(N-methylcarbamoyl)glutathione: metabolite of N-methylformamide [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID115170
SCHEMBL ID6726250
MeSH IDM0151047

Synonyms (18)

Synonym
s-(n-methylcarbamoyl)glutathione
snmcg
38126-73-7
(2s)-2-amino-5-[[(2r)-1-(carboxymethylamino)-3-(methylcarbamoylsulfanyl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
fh7d8r2r6e ,
glycine, l-gamma-glutamyl-s-((methylamino)carbonyl)-l-cysteinyl-
unii-fh7d8r2r6e
glycine, n-(n-l-gamma-glutamyl-s-((methylamino)carbonyl)-l-cysteinyl)-
l-gamma-glutamyl-s-((methylamino)carbonyl)-l-cysteinylglycine
SCHEMBL6726250
DTXSID90191537
s-(n-methylcarbamoyl) glutathione
glycine, n-(n-l-.gamma.-glutamyl-s-((methylamino)carbonyl)-l-cysteinyl)-
(2s)-2-amino-5-(((1r)-2-(carboxymethylamino)-1-(methylcarbamoylsulfanylmethyl)-2-oxo-ethyl)amino)-5-oxo-pentanoic acid
laromustine metabolite m4
l-.gamma.-glutamyl-s-((methylamino)carbonyl)-l-cysteinylglycine
s-(n-methylcarbamoyl)gsh
glycine, l-.gamma.-glutamyl-s-((methylamino)carbonyl)-l-cysteinyl-

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" To study the mechanism of this toxicity, suspensions of mouse hepatocytes were tested as an in vitro model system suitable for the study of the relationship between (i) the toxic potential of formamides, (ii) their metabolism to N-alkylcarbamoylating species, and (iii) their ability to deplete hepatic glutathione pools."( Cytotoxicity and metabolism of the hepatotoxin N-methylformamide and related formamides in mouse hepatocytes.
Gescher, A; Mráz, J; Shaw, AJ, 1988
)
0.27
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (37.50)18.7374
1990's5 (62.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.26

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.26 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.56 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.26)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]