Compounds > rutaevin

Page last updated: 2024-12-08

rutaevin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

rutaevin: from root bark of Dictamnus daycarpus Turcz. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Flora	Rank	Flora Definition	Family	Family Definition
Dictamnus	genus	A plant genus of the family RUTACEAE. Members contain eudesmane type SESQUITERPENES; COUMARINS, and obacunone (a limonoid).[MeSH]	Rutaceae	A plant family in the order Sapindales that grows in warmer regions and has conspicuous flowers.[MeSH]

Cross-References

ID Source	ID
PubMed CID	441805
CHEMBL ID	402437
CHEBI ID	8919
MeSH ID	M0213922

Synonyms (13)

Synonym
33237-37-5
rutaevin
C08779 ,
chebi:8919 ,
CHEMBL402437 ,
AC1L9BP1 ,
ambap33237-37-5
evodinone
Q27108190
(1r,2r,7s,10r,12r,13s,14r,16s,19s,20s)-19-(furan-3-yl)-12-hydroxy-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.02,7.02,10.014,16.014,20]docosane-5,11,17-trione
DTXSID40954876
12-(furan-3-yl)-8-hydroxy-6,6,8a,12a-tetramethyldecahydro-1h,3h-oxireno[c]pyrano[4'',3'':2',3']furo[3',4':5,6]naphtho[1,2-d]pyran-3,7,10(8h,9ah)-trionato
E88594

Research Excerpts

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

Class	Description
steroid lactone
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (2)

Assay ID	Title	Year	Journal	Article
AID328119	Neuroprotective activity against rat cortical cells at 10.0 uM assessed as glutamate-induced neurotoxicity by MTT assay	2008	Journal of natural products, Feb, Volume: 71, Issue:2	Neuroprotective limonoids of root bark of Dictamnus dasycarpus.
AID328116	Neuroprotective activity against rat cortical cells assessed as glutamate-induced neurotoxicity by MTT assay	2008	Journal of natural products, Feb, Volume: 71, Issue:2	Neuroprotective limonoids of root bark of Dictamnus dasycarpus.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	1 (16.67)	18.2507
2000's	1 (16.67)	29.6817
2010's	3 (50.00)	24.3611
2020's	1 (16.67)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	6 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
quinazolines Quinazolines: A group of aromatic heterocyclic compounds that contain a bicyclic structure with two fused six-membered aromatic rings, a benzene ring and a pyrimidine ring.. quinazoline : A mancude organic heterobicyclic parent that is naphthalene in which the carbon atoms at positions 1 and 3 have been replaced by nitrogen atoms.. quinazolines : Any organic heterobicyclic compound based on a quinazoline skeleton and its substituted derivatives.	2.1	1	0	azaarene; mancude organic heterobicyclic parent; ortho-fused heteroarene; quinazolines
glucose, (beta-d)-isomer beta-D-glucose : D-Glucopyranose with beta configuration at the anomeric centre.. (1->4)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->4) linkages.. (1->3)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->3) linkages.	3.03	1	0	D-glucopyranose	epitope; mouse metabolite
rutecarpine rutacarpine: from Evodia rutaecarpa; an ingredient in zhuyu hewei zhitong capsules	2.1	1	0	beta-carbolines
dictamnine dictamnine: furanoquinoline alkaloid; crosslinks DNA in presence of ultraviolet light	3.03	1	0	alkaloid antibiotic; organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
inermin inermin: phytoalexin produced in plants after injection with fungi; RN given refers to (cis-(+-))-isomer; RN for cpd without isomeric designation; structure. (-)-maackiain : The (-)-enantiomer of maackiain.	3.03	1	0	maackiain
obacunone obacunone: from bark of Chinese plant Phellodendron amurense; shortens sleeping time induced in mice by alpha-chloralose-urethane	3.39	2	0	limonoid
fraxinellone fraxinellone: structure given in first source; RN given for (3R-cis)-isomer	3.39	2	0	2-benzofurans
evodiamine [no description available]	2.1	1	0	beta-carbolines
limonin [no description available]	3.69	3	0	epoxide; furans; hexacyclic triterpenoid; lactone; limonoid; organic heterohexacyclic compound	inhibitor; metabolite; volatile oil component
benzofurans Benzofurans: Compounds that contain a BENZENE ring fused to a furan ring.	3.03	1	0
trifolirhizin trifolirhizin: from Sophora flavescens; has inhibitory effect on tyrosinase and melanin synthesis; structure in first source	3.03	1	0	pterocarpans
dizocilpine maleate Dizocilpine Maleate: A potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) used mainly as a research tool. The drug has been considered for the wide variety of neurodegenerative conditions or disorders in which NMDA receptors may play an important role. Its use has been primarily limited to animal and tissue experiments because of its psychotropic effects.. dizocilpine maleate : A maleate salt obtained by reaction of dizocilpine with one equivalent of maleic acid.	2.04	1	0	maleate salt; tetracyclic antidepressant	anaesthetic; anticonvulsant; neuroprotective agent; nicotinic antagonist; NMDA receptor antagonist