rhinacanthin Q: isolated from Rhinacanthus nasutus; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Rhinacanthus | genus | [no description available] | Acanthaceae | A plant family of the order Lamiales. It is characterized by simple leaves in opposite pairs, cystoliths (enlarged cells containing crystals of calcium carbonate), and bilaterally symmetrical and bisexual flowers that are usually crowded together. The common name for Ruellia of wild petunia is easily confused with PETUNIA.[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 10005113 |
| CHEMBL ID | 184182 |
| MeSH ID | M0300767 |
| Synonym |
|---|
| CHEMBL184182 |
| rhinacanthin q |
| [3-(1-hydroxy-3,4-dioxonaphthalen-2-yl)-2,2-dimethylpropyl] 1,4-dimethoxynaphthalene-2-carboxylate |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID247934 | Concentration required to inhibit growth of human epidermoid carcinoma (KB) cell line | 2004 | Journal of medicinal chemistry, Aug-26, Volume: 47, Issue:18 | Synthesis of novel rhinacanthins and related anticancer naphthoquinone esters. |
| AID247834 | Concentration required to inhibit growth of african green monkey kidney cell line | 2004 | Journal of medicinal chemistry, Aug-26, Volume: 47, Issue:18 | Synthesis of novel rhinacanthins and related anticancer naphthoquinone esters. |
| AID248059 | Concentration required to inhibit growth of human hepatocellular carcinoma (HepG2) cell line | 2004 | Journal of medicinal chemistry, Aug-26, Volume: 47, Issue:18 | Synthesis of novel rhinacanthins and related anticancer naphthoquinone esters. |
| AID310945 | Cytotoxicity against human KB cells | 2007 | Bioorganic & medicinal chemistry, May-15, Volume: 15, Issue:10 | 2D-autocorrelation descriptors for predicting cytotoxicity of naphthoquinone ester derivatives against oral human epidermoid carcinoma. |
| AID247933 | Concentration required to inhibit growth of human cervical carcinoma (HeLa) cell line | 2004 | Journal of medicinal chemistry, Aug-26, Volume: 47, Issue:18 | Synthesis of novel rhinacanthins and related anticancer naphthoquinone esters. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.90) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||