Page last updated: 2024-12-05

quinhydrone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Quinhydrone is a 1:1 molecular complex of hydroquinone and benzoquinone. It is a dark green, crystalline solid with a melting point of 171 °C. Quinhydrone is formed by the reaction of hydroquinone and benzoquinone in solution. The reaction is reversible, and the equilibrium constant for the formation of quinhydrone is about 10^4. Quinhydrone is used as a redox indicator in analytical chemistry. It is also used in the synthesis of other organic compounds. Quinhydrone is a powerful electron acceptor and can form charge-transfer complexes with a variety of molecules. It is also a good reducing agent and has been used to reduce a variety of organic compounds. Quinhydrone has been studied for its potential as a therapeutic agent. It has been shown to have antioxidant, anti-inflammatory, and anticancer activities. Quinhydrone is also being investigated for its potential use in the development of new energy storage devices. Quinhydrone is a versatile compound that has a wide range of applications. It is an important tool for organic synthesis and analytical chemistry. It also has potential therapeutic and energy storage applications.'

quinhydrone: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID7801
CHEBI ID26491
SCHEMBL ID51208
MeSH IDM0045716

Synonyms (38)

Synonym
nsc 36325
chinhydron [czech]
einecs 203-387-6
LS-14052
p-benzoquinone-hydroquinone compound (1:1)
106-34-3
nsc-36325
wln: l6v dvj & qr dq
quinhydrone
nsc36325
.beta.-quinhydrone
green hydroquinone
p-benzoquinhydrone
p-benzoquinone--hydroquinone compound (1:1)
CHEBI:26491
cyclohexa-2,5-diene-1,4-dione--benzene-1,4-diol (1:1)
chinhydron
quinhydrone, 97%
benzene-1,4-diol; cyclohexa-2,5-diene-1,4-dione
Q0008
AKOS009159488
unii-p4a66lq3qj
p4a66lq3qj ,
FT-0645577
quinhydrone [mi]
2,5-cyclohexadiene-1,4-dione compd with 1,4-benzenediol (1:1)
SCHEMBL51208
DTXSID9059337
W-108768
mfcd00010310
quinhydrone, puriss.
quinhydrone, 97.5%
benzoquinone compound with hydroquinone (1:1)
Q3675005
benzoquinone-hydroquinone
benzene-1,4-diol;cyclohexa-2,5-diene-1,4-dione
CS-0198853
EN300-31201

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" These results are consistent with the hypothesis that Np(V), when given in small mass quantities to fed animals, is reduced in the gastrointestinal tract to Np(IV), which is less well absorbed than Np(V)."( Effects of fasting and/or oxidizing and reducing agents on absorption of neptunium from the gastrointestinal tract of mice and adult or neonatal rats.
Ruemmler, PS; Ryan, JL; Sullivan, MF, 1984
)
0.27
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
addition compoundAn addition compound contains two or more simpler compounds that can be packed in a definite ratio into a crystal. The term covers donor-acceptor complexes (adducts) and a variety of lattice compounds.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (20)

TimeframeStudies, This Drug (%)All Drugs %
pre-19907 (35.00)18.7374
1990's0 (0.00)18.2507
2000's7 (35.00)29.6817
2010's5 (25.00)24.3611
2020's1 (5.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 43.44

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index43.44 (24.57)
Research Supply Index3.14 (2.92)
Research Growth Index4.27 (4.65)
Search Engine Demand Index61.68 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (43.44)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (4.55%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other21 (95.45%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]