Assay ID | Title | Year | Journal | Article |
AID99748 | In vitro inhibition of recombinant human leukotriene A4 hydrolase. | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6
| Synthesis of imidazopyridines and purines as potent inhibitors of leukotriene A4 hydrolase. |
AID99749 | Inhibition of leukotriene A4 hydrolase in human recombinant assay | 2002 | Bioorganic & medicinal chemistry letters, Dec-02, Volume: 12, Issue:23
| Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A(4) hydrolase. |
AID138599 | Percent inhibition was determined at a dose of 10 mg/Kg in mouse ex vivo assay | 2000 | Journal of medicinal chemistry, Feb-24, Volume: 43, Issue:4
| Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase. |
AID223081 | Inhibitory activity was determined for LTB4 production in human whole blood. | 2000 | Journal of medicinal chemistry, Feb-24, Volume: 43, Issue:4
| Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase. |
AID138548 | Ex vivo inhibition of LTB4 production in mouse whole blood at 10 mg/kg | 2002 | Bioorganic & medicinal chemistry letters, Dec-02, Volume: 12, Issue:23
| Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A(4) hydrolase. |
AID92873 | Inhibition of LTB4 production from whole human blood. | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6
| Synthesis of imidazopyridines and purines as potent inhibitors of leukotriene A4 hydrolase. |
AID99747 | Inhibitory activity was determined against Leukotriene A4 hydrolase | 2000 | Journal of medicinal chemistry, Feb-24, Volume: 43, Issue:4
| Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase. |
AID92878 | Inhibition of leukotriene B4 production in human whole blood | 2002 | Bioorganic & medicinal chemistry letters, Dec-02, Volume: 12, Issue:23
| Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A(4) hydrolase. |
AID116343 | Ex vivo inhibition of LTB4 production in mouse whole blood following 10 mg/kg p.o. administration. | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6
| Synthesis of imidazopyridines and purines as potent inhibitors of leukotriene A4 hydrolase. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |