Page last updated: 2024-12-09

pyrrolezanthine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

pyrrolezanthine: isolated from the stem wood of Formosan Zanthoxylum simulans; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
ZanthoxylumgenusA plant genus of the family RUTACEAE. Some members of Zanthoxylum are reclassified from ELEUTHEROCOCCUS, Melicope, and EVODIA. The twigs are used as dental brushing sticks (TOOTHBRUSHING). Most plants that are called Fagara have been reclassified as Zanthoxylum, however some Fagara were reclassified to MELICOPE (also in the Rutacea family) or to GLEDITSIA (a genus in the FABACEAE family).[MeSH]RutaceaeA plant family in the order Sapindales that grows in warmer regions and has conspicuous flowers.[MeSH]

Cross-References

ID SourceID
PubMed CID636825
CHEMBL ID3357678
MeSH IDM0448814

Synonyms (8)

Synonym
5-hydroxymethyl-1-[2-(4-hydroxy-phenyl)-ethyl]-1h-pyrrole-2-carbaldehyde
1h-pyrrole-2-carboxaldehyde, 5-(hydroxymethyl)-1-[2-(4-hydroxyphenyl)ethyl]-
5-hydroxymethyl-1-[2-(4-hydroxyphenyl)-ethyl]-1h-pyrrole-2-carbaldehyde
5-(hydroxymethyl)-1-[2-(4-hydroxyphenyl)ethyl]-1h-pyrrole-2-carbaldehyde
inchi=1/c14h15no3/c16-9-12-3-4-13(10-17)15(12)8-7-11-1-5-14(18)6-2-11/h1-6,9,17-18h,7-8,10h
pyrrolezanthine
5-(hydroxymethyl)-1-[2-(4-hydroxyphenyl)ethyl]pyrrole-2-carbaldehyde
CHEMBL3357678
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID1171501Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 100 uM2014Journal of natural products, Dec-26, Volume: 77, Issue:12
Jiangrines A-F and jiangolide from an actinobacterium, Jiangella gansuensis.
AID1171503Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS-challenge measured after 24 hrs by Greiss assay2014Journal of natural products, Dec-26, Volume: 77, Issue:12
Jiangrines A-F and jiangolide from an actinobacterium, Jiangella gansuensis.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 13.28

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index13.28 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index5.08 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (13.28)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]