Page last updated: 2024-11-05

pyrolan

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

pyrolan: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6888
CHEMBL ID1610900
SCHEMBL ID499894
MeSH IDM0053577

Synonyms (53)

Synonym
carbamic acid, dimethyl-, 3-methyl-1-phenyl-1h-pyrazol-5-yl ester
dimethylcarbamic acid 3-methyl-1-phenyl-1h-pyrazol-5-yl ester
1-fenyl-3-methyl-5-pyrazolylester kyseliny dimethylkarbaminove [czech]
pyrazol-5-ol, 3-methyl-1-phenyl-, dimethyl carbamate (ester)
epa pesticide chemical code 574200
carbamic acid, dimethyl-, 3-methyl-1-phenylpyrazol-5-yl ester
nsc 404297
caswell no. 574a
ai3-17588
brn 0217907
oms 20
87-47-8
1-phenyl-3-methyl-5-pyrazolyl n,n-dimethyl carbamate
mls000757184 ,
3-methyl-1-phenyl-5-pyrazolyl dimethyl carbamate
3-methyl-1-phenylpyrazol-5-yl dimethylcarbamate
wln: t5nnj ar& c1 eovn1&1
carbamic acid, 3-methyl-1-phenyl-1h-pyrazol-5-yl ester
nsc-404297
3-methyl-1-phenylpyrazol-5-yl dimethyl carbamate
g-22008
pyrazol-5-ol, dimethyl carbamate (ester)
g 22008
carbamic acid, 3-methyl-1-phenylpyrazol-5-yl ester
pyralan
ent 17,588
dimethylcarbamic acid, 3-methyl-1-phenylpyrazol-5-yl ester
geigy g-22008
dimethyl 5-(3-methyl-1-phenylpyrazolyl) carbamate
pyrolan
nsc404297
smr000529036
(5-methyl-2-phenylpyrazol-3-yl) n,n-dimethylcarbamate
1-phenyl-3-methyl-5-pyrazolyl dimethylcarbamate
NCGC00246807-01
HMS2886O15
1-fenyl-3-methyl-5-pyrazolylester kyseliny dimethylkarbaminove
unii-868k72c292
868k72c292 ,
pyrolan [mi]
3-methyl-1-phenyl-5-pyrazolyl dimethylcarbamate
n,n-dimethylcarbamic acid 3-methyl-1-phenyl-1h-pyrazol-5-yl ester
ent-17588
SCHEMBL499894
carbamic acid, dimethyl-, 5-methyl-2-phenyl-pyrazol-3-yl ester
pyrazol-5-ol, 3-methyl-1-phenyl-, dimethyl carbamate
GEDIWDLJKRKBFT-UHFFFAOYSA-N
3-methyl-1-phenyl-1h-pyrazol-5-yl dimethylcarbamate #
CHEMBL1610900
pyrolan.
DTXSID6042361
Q27269716
AKOS040747322
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (4)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
importin subunit beta-1 isoform 1Homo sapiens (human)Potency6.51315.804836.130665.1308AID540253
snurportin-1Homo sapiens (human)Potency6.51315.804836.130665.1308AID540253
GTP-binding nuclear protein Ran isoform 1Homo sapiens (human)Potency6.51315.804816.996225.9290AID540253
gemininHomo sapiens (human)Potency6.51310.004611.374133.4983AID624296
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (13)

Assay IDTitleYearJournalArticle
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 50.64

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index50.64 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.36 (4.65)
Search Engine Demand Index76.15 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (50.64)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]