pyridoxylideneglutamate profile

pyridoxylideneglutamate: in conjunction with technetium it is a hepatobiliary radiopharmaceutical; see also record for technetium Tc 99m pyridoxylidene glutamate; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	161003
SCHEMBL ID	9744784
MeSH ID	M0057139

Synonym
pyridoxylideneglutamate
13934-03-7
l-glutamic acid, n-((3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl)methylene)-
pyridoxyl glutamic acid
pyridoxylidene glutamate
(s)-2-(((3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)amino)pentanedioic acid
SCHEMBL9744784
AKOS030230723
(s,e)-2-(((3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)amino)pentanedioic acid
(2s)-2-[[3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl]methylideneamino]pentanedioic acid
(s)-2-(((3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)amino)pentanedioicacid
CS-0079274
HY-120831

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	16 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	1 (6.25%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	3 (18.75%)	4.05%
Observational	0 (0.00%)	0.25%
Other	12 (75.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
thioctic acid Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.	1.95	1	0	dithiolanes; heterocyclic fatty acid; thia fatty acid	fundamental metabolite; geroprotector
pyridoxal [no description available]	5.48	16	1	hydroxymethylpyridine; methylpyridines; monohydroxypyridine; pyridinecarbaldehyde; vitamin B6	cofactor; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
technetium Technetium: The first artificially produced element and a radioactive fission product of URANIUM. Technetium has the atomic symbol Tc, and atomic number 43. All technetium isotopes are radioactive. Technetium 99m (m=metastable) which is the decay product of Molybdenum 99, has a half-life of about 6 hours and is used diagnostically as a radioactive imaging agent. Technetium 99 which is a decay product of technetium 99m, has a half-life of 210,000 years.	5.48	16	1	manganese group element atom
bilirubin [no description available]	1.95	1	0	biladienes; dicarboxylic acid	antioxidant; human metabolite; mouse metabolite
sulfur Sulfur: An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.	1.95	1	0	chalcogen; nonmetal atom	macronutrient

Condition	Relationship Strength	Studies	Trials
Empyema, Gall Bladder [description not available]	4.44	5	1
Bile Duct Obstruction [description not available]	2.64	3	0
Gall Bladder Diseases [description not available]	2.64	3	0
Acute Disease Disease having a short and relatively severe course.	3.75	2	1
Cholecystitis Inflammation of the GALLBLADDER; generally caused by impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, or other diseases.	9.44	5	1
Cholestasis Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).	2.64	3	0
Gallstone Disease [description not available]	4.25	4	1
Cholelithiasis Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS).	4.25	4	1
Bile Duct Obstruction, Extrahepatic [description not available]	1.95	1	0
Abdominal Cramps [description not available]	3.34	1	1
Liver Dysfunction [description not available]	2.87	4	0
Liver Diseases Pathological processes of the LIVER.	2.87	4	0
Abnormality, Heart [description not available]	1.95	1	0
Intraventricular Septal Defects [description not available]	1.95	1	0
Symptom Cluster [description not available]	1.95	1	0
Situs Inversus A congenital abnormality in which organs in the THORAX and the ABDOMEN are opposite to their normal positions (situs solitus) due to lateral transposition. Normally the STOMACH and SPLEEN are on the left, LIVER on the right, the three-lobed right lung is on the right, and the two-lobed left lung on the left. Situs inversus has a familial pattern and has been associated with a number of genes related to microtubule-associated proteins.	1.95	1	0
Heart Defects, Congenital Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.	1.95	1	0
Heart Septal Defects, Ventricular Developmental abnormalities in any portion of the VENTRICULAR SEPTUM resulting in abnormal communications between the two lower chambers of the heart. Classification of ventricular septal defects is based on location of the communication, such as perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular defect.	1.95	1	0
Syndrome A characteristic symptom complex.	1.95	1	0
Biliary Tract Diseases Diseases in any part of the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.	8.05	5	0
Icterus [description not available]	2.64	3	0
Jaundice A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.	2.64	3	0
Cyst [description not available]	6.95	1	0
Biliary Calculi [description not available]	1.95	1	0
Bile Duct Cancer [description not available]	1.95	1	0
Cancer of Gallbladder [description not available]	1.95	1	0
Cancer of Pancreas [description not available]	1.95	1	0
Bile Duct Neoplasms Tumors or cancer of the BILE DUCTS.	1.95	1	0
Gallbladder Neoplasms Tumors or cancer of the gallbladder.	1.95	1	0
Pancreatic Neoplasms Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).	1.95	1	0
Gallstones Solid crystalline precipitates in the BILIARY TRACT, usually formed in the GALLBLADDER, resulting in the condition of CHOLELITHIASIS. Gallstones, derived from the BILE, consist mainly of calcium, cholesterol, or bilirubin.	1.95	1	0

pyridoxylideneglutamate

Description

Cross-References

Synonyms (13)

Research

Studies (16)

Market Indicators

Research Demand Index: 11.56

Study Types