Page last updated: 2024-10-15

pterine-6-carboxylic acid

Description

pterine-6-carboxylic acid: photodegradation product of folic acid [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID135403803
CHEMBL ID566727
CHEBI ID88937
SCHEMBL ID893092
SCHEMBL ID13820952
MeSH IDM0358824

Synonyms (69)

Synonym
DIVK1C_006891
SPECTRUM_000242
SPECTRUM4_001713
BSPBIO_003326
SPECTRUM5_000446
948-60-7
nsc-96893
nsc96893
KBIOGR_002066
KBIO3_002546
KBIOSS_000722
KBIO2_000722
KBIO2_005858
KBIO2_003290
KBIO1_001835
SPBIO_001861
SPECTRUM3_001713
SPECTRUM2_001821
SPECPLUS_000795
NCGC00178139-01
pterine-6-carboxylic acid, >=98.0% (hplc)
ranachrome 5
HHS ,
6-carboxypterin ,
2-amino-4-oxo-1h-pteridine-6-carboxylic acid
pterin-6-carboxylic acid
chebi:88937 ,
CHEMBL566727
A809012
1501-50-4
2-AMINO-4-HYDROXY-6-PTERIDINECARBOXYLIC ACID ,
2-amino-4-hydroxypteridine-6-carboxylic acid
2-amino-1,4-dihydro-4-oxopteridine-6-carboxylic acid
nsc 96893
unii-2g01j4lz8y
einecs 213-435-8
2g01j4lz8y ,
CCG-38452
2-amino-4-hydroxypteridine-6-carboxylicacid
pterine-6-carboxylic acid
FT-0633615
AKOS015910901
SCHEMBL893092
SCHEMBL13820952
QABAUCFGPWONOG-UHFFFAOYSA-N
2-amino-4-oxo-3,4-dihydro-6-pteridinecarboxylic acid #
6-pteridinecarboxylic acid, 2-amino-1,4-dihydro-4-oxo-
2-amino-4-keto-1h-pteridine-6-carboxylic acid
pterin-6-carboxylicacid
mfcd00010594
DTXSID30241626
2-amino-4(3h)-pteridinone-6-carboxylic acid
2-amino-4-oxo-3,4-dihydro-6-pteridinecarboxylic acid
2-amino-1,4-dihydro-4-oxo-6-pteridinecarboxylic acid
'2-amino-4-oxo-3,4-dihydropteridine-6-carboxylic acid'
Q27161007
6-car-boxypterin
2-amino-4-hydroxypterin-6-carboxylic acid
2-amino-6-carboxy-4-hydroxypteridine
2-amino-3,4-dihydro-4-oxo-6-pteridinecarboxylic acid
2-amino-4-hydroxy-6-carboxypteridine
6-pteridinecarboxylic acid, 2-amino-4-hydroxy-
2-amino-4-oxo-3h-pteridine-6-carboxylic acid
2-amino-4-oxo-3,4-dihydropteridine-6-carboxylic acid
CS-0094339
2-amino-4-oxo-3,4-dihydropteridine-6-carboxylicacid
GEO-04483
F87135
AKOS040763764
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
organooxygen compoundAn organochalcogen compound containing at least one carbon-oxygen bond.
organonitrogen compoundAny heteroorganic entity containing at least one carbon-nitrogen bond.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (7)

Assay IDTitleYearJournalArticle
AID444559Inhibition of Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) at 500 uM after 30 mins2010Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1
Structural studies of pterin-based inhibitors of dihydropteroate synthase.
AID977599Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID977602Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID444560Inhibition of Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 mins2010Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1
Structural studies of pterin-based inhibitors of dihydropteroate synthase.
AID1713572Inhibition of recombinant human ALR2 using D,L-glyceraldehyde and NADPH as substrate preincubated for 3 mins followed by substrate addition and measured for 3 mins by spectrophotometric analysis2016Bioorganic & medicinal chemistry letters, 10-15, Volume: 26, Issue:20
Pterin-7-carboxamides as a new class of aldose reductase inhibitors.
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
AID1159550Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening2015Nature cell biology, Nov, Volume: 17, Issue:11
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (16)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's5 (31.25)29.6817
2010's10 (62.50)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (5.26%)5.53%
Reviews1 (5.26%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other17 (89.47%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]