Page last updated: 2024-12-10

pregna-1,4-diene-11-ol-3,20-dione

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

pregna-1,4-diene-11-ol-3,20-dione: RN given refers to 11beta-isomer in Chemline; RN for unspecified isomer not in Chemline 7/11/83 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID3080605
SCHEMBL ID11044326
MeSH IDM0115618

Synonyms (8)

Synonym
pregna-1,4-diene-11-ol-3,20-dione
pregna-1,4-diene-3,20-dione, 11-hydroxy-, (11beta)-
delta-hop
(8s,9s,10r,11s,13s,14s,17s)-17-acetyl-11-hydroxy-10,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
4224-37-7
SCHEMBL11044326
DTXSID40962390
11-hydroxypregna-1,4-diene-3,20-dione

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" In contrast, glucocorticoids produced the classical dose-response inhibition and the effect persisted when they were removed from the cultured medium."( Inhibitory effect of 11 beta-hydroxypregna-1,4-diene-3,20-dione (delta HOP) on lymphocyte proliferation.
Castillo, MB; Roldán, A; Rondinone, CM; Schillaci, R, 1991
)
0.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.46

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.46 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.25 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.46)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]