Compounds > piperonyl alcohol
Page last updated: 2024-12-05

piperonyl alcohol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

piperonyl alcohol: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID10322
CHEBI ID167431
SCHEMBL ID49914
MeSH IDM0123332

Synonyms (66)

Synonym
einecs 207-808-4
benzyl alcohol, 3,4-(methylenedioxy)-
unii-4163k563gs
4163k563gs ,
hsdb 8494
heliotropyl alcohol
nsc 26265
ai3-05702
CHEBI:167431
1,3-benzodioxol-5-yl-methanol
nsc26265
nsc-26265
benzyl alcohol,4-(methylenedioxy)-
piperonol
piperonyl alcohol
1-hydroxymethyl-3,4-methylenedioxybenzene
1,3-benzodioxole-5-methanol
3,4-methylenedioxybenzyl alcohol
495-76-1
5-hydroxymethyl-1,3-benzodioxole
SDCCGMLS-0065920.P001
benzo[1,3]dioxol-5-ylmethanol
DALC2-H_000040
1,3-benzodioxol-5-ylmethanol
AP-065/40214405
inchi=1/c8h8o3/c9-4-6-1-2-7-8(3-6)11-5-10-7/h1-3,9h,4-5h
piperonyl alcohol, 98%
STK397489
P0457
helioalcohol
(1,3-benzodioxol-5-yl)methanol
AKOS000119342
BBL011934
AM803952
benzo[d][1,3]dioxol-5-ylmethanol
FT-0614397
3,4-(methylenedioxy)benzenemethanol
benzo(1,3)dioxol-5-ylmethanol
3,4-methylenedioxyphenylmethanol
(benzodioxol-5-yl)methanol
SCHEMBL49914
(2h-1,3-benzodioxol-5-yl)methanol
FS-1186
3,4 -methylendioxy-benzylalcohol
3,4-methylenedioxyphenyl methanol
3,4-(methylenedioxy)-benzyl alcohol
3,4-(methylenedioxy)benzyl alcohol
benzo[1,3]dioxol-5-yl-methanol
3,4-(methylenedioxy)phenylmethanol
benz[1,3]dioxol-5-yl-methanol
3,4-methylendioxy-benzylalcohol
3,4-methylendioxybenzylalcohol
3,4-methylenedioxy-benzyl alcohol
3,4-methylenedioxy benzyl alcohol
DTXSID3060089
piperonylalkohol
F0001-1287
mfcd00005836
piperonylalcohol
SY033132
1,3-benzodioxol-5-ylmethanol; helioalcohol
(1,3-dioxaindan-5-yl)methanol
EN300-20232
5-(hydroxymethyl)-1,3-benzodioxole
Q27258401
Z104477372

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" With worker ants the toxic effects started with compound 5 and increased with the number of carbons in the side chain."( Toxicity of synthetic piperonyl compounds to leaf-cutting ants and their symbiotic fungus.
Bacci Júnior, M; Bueno, FC; Bueno, OC; Correa, AG; Crisóstomo, FR; da Silva, MF; Fernandes, JB; Hebling, MJ; Pagnocca, FC; Victor, SR; Vieira, PC, 2001)		0.31
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
benzodioxoles
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).2014Journal of biomolecular screening, Jul, Volume: 19, Issue:6
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 33.43

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index33.43 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.46 (4.65)
Search Engine Demand Index42.09 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (33.43)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
bromide
Bromides: Salts of hydrobromic acid, HBr, with the bromine atom in the 1- oxidation state. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)		210halide anion;
monoatomic bromine
camphor, (+-)-isomer
[no description available]		2.1710bornane monoterpenoid;
cyclic monoterpene ketone		plant metabolite
4-aminobenzoic acid
para-Aminobenzoates: Benzoic acids, salts, or esters that contain an amino group attached to carbon number 4 of the benzene ring structure.. 4-aminobenzoate : An aromatic amino-acid anion that is the conjugate base of 4-aminobenzoic acid.		2.1710aminobenzoate;
aromatic amino-acid anion		Escherichia coli metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
piperonyl butoxide
[no description available]		210benzodioxolespesticide synergist
triethylene glycol dimethacrylate
[no description available]		2.1710
piperonal
piperonal: has been used as a pediculicide; structure. piperonal : An arenecarbaldehyde that is 1,3-benzodioxole substituted by a formyl substituent at position 5. It has been isolated from Piper nigrum.		6.9610arenecarbaldehyde;
benzodioxoles		fragrance;
insect repellent;
plant metabolite
1,3-benzodioxole
1,3-benzodioxole : A benzodioxole consisting of a benzene ring substituted by a the methylenedioxy group.		2.1710benzodioxole
oxazoles
Oxazoles: Five-membered heterocyclic ring structures containing an oxygen in the 1-position and a nitrogen in the 3-position, in distinction from ISOXAZOLES where they are at the 1,2 positions.. 1,3-oxazole : A five-membered monocyclic heteroarene that is an analogue of cyclopentadiene with O in place of CH2 at position 1 and N in place of CH at position 3.. oxazole : An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom.		2.21101,3-oxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
hydroxyethyl methacrylate
hydroxyethyl methacrylate: many of cited refs are for gel which refers to polymeric form of above cpd: POLYHYDROXYETHYL METHACRYLATE. 2-hydroxyethyl methacrylate : An enoate ester that is the monomethacryloyl derivative of ethylene glycol.		2.1710enoate esterallergen;
polymerisation monomer
bisphenol a-glycidyl methacrylate
Bisphenol A-Glycidyl Methacrylate: The reaction product of bisphenol A and glycidyl methacrylate that undergoes polymerization when exposed to ultraviolet light or mixed with a catalyst. It is used as a bond implant material and as the resin component of dental sealants and composite restorative materials.		2.1710diarylmethane
hymexazol
hymexazol: a chemical used to sterilize soil; structure in first source. hymexazol : A member of the class of isoxazoles carrying hydroxy and methyl substituents at positions 3 and 5 respectively. It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces, Pythium, and Corticium spp. in rice, sugarbeet, fodderbeet, vegetables, cucurbits, and ornamentals.		2.2110heteroaryl hydroxy compound;
isoxazoles		antifungal agrochemical
ethyl 4-dimethylaminobenzoate
ethyl 4-dimethylaminobenzoate: slow-acting amine polymerization accelerator. parbenate : A benzoate ester that is ethyl benzoate substituted by a dimethylamino group at position 4.		2.1710benzoate ester;
ethyl ester;
tertiary amino compound
camphoroquinone
camphoroquinone: a natural monoterpene, non-aromatic quinone; structure given in first source. bornane-2,3-dione : A bornane monoterpenoid that is bicyclo[2.2.1]heptane substituted by methyl groups at positions 1, 7 and 7 and oxo groups at positions 2 and 3.		2.1710bornane monoterpenoid;
carbobicyclic compound
iodine
[no description available]		210halide anion;
monoatomic iodine		human metabolite
burchellin
burchellin: isolated from Piper hancei Maxim; structure given in first source. burchellin : A neolignan with formula C20H20O5 that is isolated from Ocotea cymbarum and Piper wallichii. It is active against a variety of parasites including T. cruzi, the vector for Chagas disease.		2.0410
benzofurans
Benzofurans: Compounds that contain a BENZENE ring fused to a furan ring.		2.0410
ConditionIndicatedRelationship StrengthStudiesTrials
Plasmodium falciparum Malaria
[description not available]		02.110
Malaria, Falciparum
Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.		02.110
American Trypanosomiasis
[description not available]		02.0410
Chagas Disease
Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.		02.0410