Page last updated: 2024-12-07

phenylacetaldoxime

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Phenylacetaldoxime is an organic compound with the formula C8H9NO. It is a white crystalline solid that is soluble in ethanol and ether. The compound is a derivative of phenylacetaldehyde, with an oxime group replacing the aldehyde hydrogen. It has been studied for its potential as a precursor to other compounds, including pharmaceuticals and agrochemicals. The synthesis of phenylacetaldoxime typically involves the reaction of phenylacetaldehyde with hydroxylamine. One key aspect of this compound is its ability to undergo various chemical reactions. It can be converted into nitriles through a dehydration reaction, which is a common method for synthesizing nitrile-containing compounds. Furthermore, phenylacetaldoxime can be used to synthesize various nitrogen-containing heterocycles. The potential applications of phenylacetaldoxime in different fields, such as pharmaceuticals, agrochemicals, and materials science, have attracted significant research interest. While the compound itself might not have direct pharmaceutical applications, its derivatives have shown promising biological activity. For instance, some derivatives of phenylacetaldoxime have exhibited anti-inflammatory and analgesic properties. The compound's reactivity and its potential for derivatization make it a valuable starting material for exploring new chemical entities with desired properties. Additionally, its ability to undergo reactions involving nitrogen atoms makes it a potential building block for synthesizing nitrogen-containing polymers and other materials. Despite its potential, research on phenylacetaldoxime remains limited, and further investigation is required to fully understand its properties and applications. This includes exploring the potential biological activity of its derivatives and investigating its role in material science.'

phenylacetaldehyde oxime : An aldoxime resulting from the formal condensation of the aldehyde moiety of phenylacetaldehyde with hydroxylamine. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID99748
CHEBI ID47791
SCHEMBL ID265957
MeSH IDM0363693

Synonyms (15)

Synonym
nsc 203259
einecs 230-309-8
brn 2040645
benzeneacetaldehyde, oxime
phenylacetaldehyde oxime
phenylacetaldoxime ,
CHEBI:47791
phenylethanal oxime
4-07-00-00665 (beilstein handbook reference)
SCHEMBL265957
benzylnitrone
phenyl acetaldehyde oxime
anti-phenylacetaldoxime
phenylacetal-dehyde oxime
Q27120790
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
aldoximeOximes of aldehydes RCH=NOH.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's5 (50.00)24.3611
2020's1 (10.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 19.97

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index19.97 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.73 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (19.97)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]