Page last updated: 2024-12-07
phenylacetaldoxime
Description
Phenylacetaldoxime is an organic compound with the formula C8H9NO. It is a white crystalline solid that is soluble in ethanol and ether. The compound is a derivative of phenylacetaldehyde, with an oxime group replacing the aldehyde hydrogen. It has been studied for its potential as a precursor to other compounds, including pharmaceuticals and agrochemicals. The synthesis of phenylacetaldoxime typically involves the reaction of phenylacetaldehyde with hydroxylamine. One key aspect of this compound is its ability to undergo various chemical reactions. It can be converted into nitriles through a dehydration reaction, which is a common method for synthesizing nitrile-containing compounds. Furthermore, phenylacetaldoxime can be used to synthesize various nitrogen-containing heterocycles. The potential applications of phenylacetaldoxime in different fields, such as pharmaceuticals, agrochemicals, and materials science, have attracted significant research interest. While the compound itself might not have direct pharmaceutical applications, its derivatives have shown promising biological activity. For instance, some derivatives of phenylacetaldoxime have exhibited anti-inflammatory and analgesic properties. The compound's reactivity and its potential for derivatization make it a valuable starting material for exploring new chemical entities with desired properties. Additionally, its ability to undergo reactions involving nitrogen atoms makes it a potential building block for synthesizing nitrogen-containing polymers and other materials. Despite its potential, research on phenylacetaldoxime remains limited, and further investigation is required to fully understand its properties and applications. This includes exploring the potential biological activity of its derivatives and investigating its role in material science.'
phenylacetaldehyde oxime : An aldoxime resulting from the formal condensation of the aldehyde moiety of phenylacetaldehyde with hydroxylamine. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
ID Source | ID |
PubMed CID | 99748 |
CHEBI ID | 47791 |
SCHEMBL ID | 265957 |
MeSH ID | M0363693 |
Synonyms (15)
Synonym |
nsc 203259 |
einecs 230-309-8 |
brn 2040645 |
benzeneacetaldehyde, oxime |
phenylacetaldehyde oxime |
phenylacetaldoxime , |
CHEBI:47791 |
phenylethanal oxime |
4-07-00-00665 (beilstein handbook reference) |
SCHEMBL265957 |
benzylnitrone |
phenyl acetaldehyde oxime |
anti-phenylacetaldoxime |
phenylacetal-dehyde oxime |
Q27120790 |
Drug Classes (1)
Class | Description |
aldoxime | Oximes of aldehydes RCH=NOH. |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (10)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (40.00) | 29.6817 |
2010's | 5 (50.00) | 24.3611 |
2020's | 1 (10.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 19.97
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 19.97 (24.57) | Research Supply Index | 2.40 (2.92) | Research Growth Index | 4.73 (4.65) | Search Engine Demand Index | 15.26 (26.88) | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 10 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |