Compounds > phenesterin
Page last updated: 2024-12-08

phenesterin

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Description

phenesterin: alkylating agent; major descriptor (73-83); on-line search NITROGEN MUSTARD COMPOUNDS (73-83); Index Medicus search PHENESTERIN (73-83); structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID266461
SCHEMBL ID9277
MeSH IDM0262500

Synonyms (46)

Synonym
(3beta)-cholest-5-en-3-yl {4-[bis(2-chloroethyl)amino]phenyl}acetate
cholest-5-en-3-ol (3.beta.)-, 4-[bis(2-chloroethyl)amino]benzeneacetate
nci-c01558
phenesterin
fenestrin
n-[p-[bis(2-chloroethyl)amino]phenyl]acetic acid chlestorol ester
[p-[bis(2-chloroethyl)amino]phenyl]acetic acid cholesterol ester
acetic acid, cholesteryl ester
fenesterin
nsc 104469
nsc-104 469e
phenestrin
3546-10-9
nsc-104469
fda 1553
phenesterine
cholesteryl [p-[bis(2-chloroethyl)amino]phenyl]acetate
nsc104469
cholesterol, [p-[bis(2-chloroethyl)amino]phenyl]acetate
cholest-5-en-3-ol, 4-[bis(2-chloroethyl)amino]benzeneacetate
ccris 499
5-cholesten-3-beta-ol 3-(p-(bis(2-chloroethyl)amino)phenyl)acetate
n-(p-(bis(2-chloroethyl)amino)phenyl)acetic acid chlestorol ester
cholesterol, (p-(bis(2-chloroethyl)amino)phenyl)acetate
cholest-5-en-3-ol, (3-beta)-, 4-(bis(2-chloroethyl)amino)benzeneacetate
cholest-5-en-3-ol (3beta)-, 4-(bis(2-chloroethyl)amino)benzeneacetate
cholesterol, (p-(bis(2-chloroethyl)amino)phenyl) acetate
hsdb 7076
acetic acid, (4-(bis(2-chloroethyl)amino)phenyl)-, cholesteryl ester
cholesteryl (p-(bis(2-chloroethyl)amino)phenyl)acetate
cholesteryl p-bis(2-chloroethyl)amino phenylacetate
(p-(bis(2-chloroethyl)amino)phenyl)acetic acid cholesterol ester
cholesteryl p-bis(2-chloroethyl)aminophenylacetate
[(3s,8s,9s,10r,13r,14s,17r)-10,13-dimethyl-17-[(2r)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-yl] 2-[4-[bis(2-chloroethyl)amino]phenyl]acetate
34021jc2z6 ,
unii-34021jc2z6
cholest-5-en-3-ol (3.beta.)-, 3-(4-(bis(2-chloroethyl)amino)benzeneacetate)
phenesterine [mi]
dal-25
phenesterin [hsdb]
SCHEMBL9277
cholest-5-en-3-yl (4-[bis(2-chloroethyl)amino]phenyl)acetate, (3.beta.)- #
5-cholesten-3-.beta.-ol 3-(p-(bis(2-chloroethyl)amino)phenyl)acetate
SPJCRMJCFSJKDE-ZWBUGVOYSA-N
DTXSID6021119
Q27256304
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (4)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.66 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.66)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
ConditionIndicatedRelationship StrengthStudiesTrials
Carcinoma 256, Walker
A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed)		01.9410
Carcinoma, Ehrlich Tumor
A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.		01.9410
Cancer of Liver
[description not available]		01.9410
Diffuse Mixed Small and Large Cell Lymphoma
[description not available]		01.9410
Benign Neoplasms
[description not available]		02.3420
Experimental Neoplasms
[description not available]		02.3420
Anaplastic Oligodendroglioma
[description not available]		01.9410
Sarcoma 180
An experimental sarcoma of mice.		01.9410
EHS Tumor
[description not available]		01.9410
Anaplastic Ependymoma
[description not available]		01.9410
Sarcoma 37
An experimental sarcoma of mice.		01.9410
Ependymoma
Glioma derived from EPENDYMOGLIAL CELLS that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults. It may arise from any level of the ventricular system or central canal of the spinal cord. Intracranial ependymomas most frequently originate in the FOURTH VENTRICLE and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes. Spinal ependymomas are usually benign papillary or myxopapillary tumors. (From DeVita et al., Principles and Practice of Oncology, 5th ed, p2018; Escourolle et al., Manual of Basic Neuropathology, 2nd ed, pp28-9)		01.9410
Liver Neoplasms
Tumors or cancer of the LIVER.		01.9410
Lymphoma, Non-Hodgkin
Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.		01.9410
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.		02.3420
Oligodendroglioma
A relatively slow-growing glioma that is derived from oligodendrocytes and tends to occur in the cerebral hemispheres, thalamus, or lateral ventricle. They may present at any age, but are most frequent in the third to fifth decades, with an earlier incidence peak in the first decade. Histologically, these tumors are encapsulated, relatively avascular, and tend to form cysts and microcalcifications. Neoplastic cells tend to have small round nuclei surrounded by unstained nuclei. The tumors may vary from well-differentiated to highly anaplastic forms. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2052; Adams et al., Principles of Neurology, 6th ed, p655)		01.9410
Cancer of Ovary
[description not available]		01.9610
Ovarian Neoplasms
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.		01.9610