Compounds > penfluron
Page last updated: 2024-12-07

penfluron

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Penfluron is an insecticide belonging to the fluoronicotinyl class. It acts as an insect growth regulator (IGR), interfering with the synthesis of chitin, a key component of insect exoskeletons. This disrupts their molting process and ultimately leads to their death. Penfluron is used in agricultural applications to control a wide range of insect pests, particularly on crops such as cotton, vegetables, and fruit trees. Its mode of action is distinct from conventional insecticides, making it valuable for managing resistance development. Research into penfluron focuses on its efficacy, environmental fate, and potential impacts on non-target organisms. Studies explore its persistence in soil and water, as well as its potential for bioaccumulation in food chains. The development of new formulations and application techniques aim to optimize its effectiveness while minimizing environmental risks.'

Cross-References

ID SourceID
PubMed CID107651
CHEMBL ID2229533
SCHEMBL ID117735
MeSH IDM0081831

Synonyms (22)

Synonym
penfluron
35367-31-8
2,6-difluoro-n-[[4-(trifluoromethyl)phenyl]carbamoyl]benzamide
ph 60-44
m9940344yh ,
ai3-63223
unii-m9940344yh
2,6-difluoro-n-(((4-(trifluoromethyl)phenyl)amino)carbonyl)benzamide
epa pesticide chemical code 124001
1-(2,6-difluorobenzoyl)-3-(4-trifluoro-methylphenyl)urea
benzamide, 2,6-difluoro-n-(((4-(trifluoromethyl)phenyl)amino)carbonyl)-
caswell no. 647c
AKOS015903476
CHEMBL2229533
1-(2,6-difluorobenzoyl)-3-(.alpha.,.alpha.,.alpha.-trifluoro-p-tolyl)urea
SCHEMBL117735
penfluoron
DTXSID8042262
2,6-difluoro-n-(4-(trifluoromethyl)phenylcarbamoyl)benzamide
1-(2,6-difluorobenzoyl)-3-(4-trifluoromethylphenyl)urea
Q27283715
jthmhwahaklckt-uhfffaoysa-n
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (22)

Assay IDTitleYearJournalArticle
AID1090131Insecticidal activity against fourth instar larvae of Mythimna separata (Oriental armyworm) in compound treated corn leaves assessed as mortality at 0.2 mg/kg by foliar application2005Journal of agricultural and food chemistry, Jan-12, Volume: 53, Issue:1
Synthesis and insecticidal evaluation of propesticides of benzoylphenylureas.
AID1090138Insecticidal activity against fourth instar larvae of Mythimna separata (Oriental armyworm) in compound treated corn leaves assessed as mortality at 50 mg/kg by foliar application2005Journal of agricultural and food chemistry, Jan-12, Volume: 53, Issue:1
Synthesis and insecticidal evaluation of propesticides of benzoylphenylureas.
AID1090130Insecticidal activity against fourth instar larvae of Mythimna separata (Oriental armyworm) in compound treated corn leaves assessed as mortality at 0.1 mg/kg by foliar application2005Journal of agricultural and food chemistry, Jan-12, Volume: 53, Issue:1
Synthesis and insecticidal evaluation of propesticides of benzoylphenylureas.
AID1090139Insecticidal activity against fourth instar larvae of Mythimna separata (Oriental armyworm) in compound treated corn leaves assessed as mortality at 200 mg/kg by foliar application2005Journal of agricultural and food chemistry, Jan-12, Volume: 53, Issue:1
Synthesis and insecticidal evaluation of propesticides of benzoylphenylureas.
AID1090605Larvicidal activity against Mythimna separata (Oriental armyworm ) in compound treated corn leaves at 0.5 mg/L at 25 +/- 1 degC measured after 4 days2007Journal of agricultural and food chemistry, Apr-04, Volume: 55, Issue:7
Insecticidal benzoylphenylurea-S-carbamate: a new propesticide with two effects of both benzoylphenylureas and carbamates.
AID1090608Larvicidal activity against Mythimna separata (Oriental armyworm) in compound treated corn leaves at 5 mg/L at 25 +/- 1 degC measured after 4 days2007Journal of agricultural and food chemistry, Apr-04, Volume: 55, Issue:7
Insecticidal benzoylphenylurea-S-carbamate: a new propesticide with two effects of both benzoylphenylureas and carbamates.
AID1090133Insecticidal activity against fourth instar larvae of Mythimna separata (Oriental armyworm) in compound treated corn leaves assessed as mortality at 1 mg/kg by foliar application2005Journal of agricultural and food chemistry, Jan-12, Volume: 53, Issue:1
Synthesis and insecticidal evaluation of propesticides of benzoylphenylureas.
AID1090135Insecticidal activity against fourth instar larvae of Mythimna separata (Oriental armyworm) in compound treated corn leaves assessed as mortality at 10 mg/kg by foliar application2005Journal of agricultural and food chemistry, Jan-12, Volume: 53, Issue:1
Synthesis and insecticidal evaluation of propesticides of benzoylphenylureas.
AID1090132Insecticidal activity against fourth instar larvae of Mythimna separata (Oriental armyworm) in compound treated corn leaves assessed as mortality at 0.5 mg/kg by foliar application2005Journal of agricultural and food chemistry, Jan-12, Volume: 53, Issue:1
Synthesis and insecticidal evaluation of propesticides of benzoylphenylureas.
AID1090610Larvicidal activity against Mythimna separata (Oriental armyworm) in compound treated corn leaves at 25 mg/L at 25 +/- 1 degC measured after 4 days2007Journal of agricultural and food chemistry, Apr-04, Volume: 55, Issue:7
Insecticidal benzoylphenylurea-S-carbamate: a new propesticide with two effects of both benzoylphenylureas and carbamates.
AID1090607Larvicidal activity against Mythimna separata (Oriental armyworm) in compound treated corn leaves at 2.5 mg/L at 25 +/- 1 degC measured after 4 days2007Journal of agricultural and food chemistry, Apr-04, Volume: 55, Issue:7
Insecticidal benzoylphenylurea-S-carbamate: a new propesticide with two effects of both benzoylphenylureas and carbamates.
AID1090136Insecticidal activity against fourth instar larvae of Mythimna separata (Oriental armyworm) in compound treated corn leaves assessed as mortality at 25 mg/kg by foliar application2005Journal of agricultural and food chemistry, Jan-12, Volume: 53, Issue:1
Synthesis and insecticidal evaluation of propesticides of benzoylphenylureas.
AID1090609Larvicidal activity against Mythimna separata (Oriental armyworm) in compound treated corn leaves at 10 mg/L at 25 +/- 1 degC measured after 4 days2007Journal of agricultural and food chemistry, Apr-04, Volume: 55, Issue:7
Insecticidal benzoylphenylurea-S-carbamate: a new propesticide with two effects of both benzoylphenylureas and carbamates.
AID1090134Insecticidal activity against fourth instar larvae of Mythimna separata (Oriental armyworm) in compound treated corn leaves assessed as mortality at 5 mg/kg by foliar application2005Journal of agricultural and food chemistry, Jan-12, Volume: 53, Issue:1
Synthesis and insecticidal evaluation of propesticides of benzoylphenylureas.
AID1080643Insecticidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 0.5 mg/l at 25 +/-1degC after 4 days2009Journal of agricultural and food chemistry, May-13, Volume: 57, Issue:9
Design, synthesis, and insecticidal activities of new N-benzoyl-N'-phenyl-N'-sulfenylureas.
AID1090137Insecticidal activity against fourth instar larvae of Mythimna separata (Oriental armyworm) in compound treated corn leaves assessed as mortality at 100 mg/kg by foliar application2005Journal of agricultural and food chemistry, Jan-12, Volume: 53, Issue:1
Synthesis and insecticidal evaluation of propesticides of benzoylphenylureas.
AID1090140Insecticidal activity against fourth instar larvae of Mythimna separata (Oriental armyworm) in compound treated corn leaves assessed as mortality at 500 mg/kg by foliar application2005Journal of agricultural and food chemistry, Jan-12, Volume: 53, Issue:1
Synthesis and insecticidal evaluation of propesticides of benzoylphenylureas.
AID1080644Insecticidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 1 mg/l at 25 +/-1degC after 4 days2009Journal of agricultural and food chemistry, May-13, Volume: 57, Issue:9
Design, synthesis, and insecticidal activities of new N-benzoyl-N'-phenyl-N'-sulfenylureas.
AID1090606Larvicidal activity against Mythimna separata (Oriental armyworm) in compound treated corn leaves at 1 mg/L at 25 +/- 1 degC measured after 4 days2007Journal of agricultural and food chemistry, Apr-04, Volume: 55, Issue:7
Insecticidal benzoylphenylurea-S-carbamate: a new propesticide with two effects of both benzoylphenylureas and carbamates.
AID1080642Insecticidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 0.25 mg/l at 25 +/-1degC after 4 days2009Journal of agricultural and food chemistry, May-13, Volume: 57, Issue:9
Design, synthesis, and insecticidal activities of new N-benzoyl-N'-phenyl-N'-sulfenylureas.
AID1090604Larvicidal activity against Mythimna separata (Oriental armyworm) in compound treated corn leaves at 0.25 mg/L at 25 +/- 1 degC measured after 4 days2007Journal of agricultural and food chemistry, Apr-04, Volume: 55, Issue:7
Insecticidal benzoylphenylurea-S-carbamate: a new propesticide with two effects of both benzoylphenylureas and carbamates.
AID1090611Larvicidal activity against Mythimna separata (Oriental armyworm) in compound treated corn leaves at 50 mg/L at 25 +/- 1 degC measured after 4 days2007Journal of agricultural and food chemistry, Apr-04, Volume: 55, Issue:7
Insecticidal benzoylphenylurea-S-carbamate: a new propesticide with two effects of both benzoylphenylureas and carbamates.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (62.50)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
methomyl
Methomyl: A carbamate insecticide with anticholinesterase activity.. methomyl : A carbamate ester obtained by the formal condensation of methylcarbamic acid with the hydroxy group of 1-(methylsulfanyl)acetaldoxime.		2.0310aliphatic sulfide;
carbamate ester		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
nematicide;
xenobiotic
acetylglucosamine
Acetylglucosamine: The N-acetyl derivative of glucosamine.. N-acetyl-beta-D-glucosamine : An N-acetyl-D-glucosamine having beta-configuration at the anomeric centre.		1.9610N-acetyl-D-glucosamineepitope
diflubenzuron
Diflubenzuron: An insect growth regulator which interferes with the formation of the insect cuticle. It is effective in the control of mosquitoes and flies.. diflubenzuron : A benzoylurea insecticide that is urea in which a hydrogen attached to one of the nitrogens is replaced by a 4-chlorophenyl group, and a hydrogen attached to the other nitrogen is replaced bgy a 2,6-difluorobenzoyl group.		3.2460benzoylurea insecticide;
monochlorobenzenes		insect sterilant
triflumuron
triflumuron: insect growth inhibitor		2.940aromatic ether;
benzoylurea insecticide;
monochlorobenzenes;
organofluorine compound
ConditionIndicatedRelationship StrengthStudiesTrials