Page last updated: 2024-12-05

oxydess

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID9306
SCHEMBL ID42098
MeSH IDM0485038

Synonyms (128)

Synonym
einecs 224-306-0
4298-16-2
wln: 1my1r &gh -r
(.+-.)-madrine
dl-deoxyephedrine hydrochloride
dl-methamphetaminehydrochloride
benzeneethanamine,.alpha.-dimethyl-, hydrochloride, (.+-.)-
phenethylamine,.alpha.-dimethyl-, hydrochloride, (.+-.)-
dl-desoxyephedrine hydrochloride
dl-methamphetamine hydrochloride
dl-methanphetamine hydrochloride
dl-n-methyl-.beta.-phenylisopropylamine hydrochloride
(.+-.)-methamphetamine hydrochloride
nsc-22367
nsc22367
(+-)-n-methylamphetamine hydrochloride
c 6379
methedrinal
psicopan
metamphetamin
levetamin
estimulex
methylbenzedrin
depoxin
einecs 206-093-6
(+-)-methamphetamine hydrochloride
miller drine
doxephrin
psychergine
desfedran
neodrine
desfedrin
psykoton
914f
psiquergina
norodrin
premodrin
phedrisox
methylpropamine
oxydrin
pisichergina
phenethylamine, n,alpha-dimethyl-, hydrochloride
dea oxo-5
amphedroxyn
kemodrin
nsc 22367
methamphin
oxyfed
methamphetamine hydrochloride, (dl)
noradrin
neopharmedrine
mepho-d
nsc 169506
dopidrin
semoxydrine
phedoxe
oxydrene
lanazine
n-methyl-beta-phenylisopropylaminhydrochlorid [german]
oxydess
psichergina
amedrine
doxephin
bombita
daropervamin
normadrine
metamsustac
n,alpha-dimethylphenethylamine hydrochloride
amdram
desossiefedrina
dexophrine
methoxyn
amphedroxy
fenyprin
deoxyphedrine
(+)-n,.alpha.-dimethylphenethylamine hydrochloride
(+)-metamphetamine hydrochloride
nsc-169506
dexoval hydrochloride
usaf el-36
methedrine
d-n-methyl-.beta.-phenylisopropylamine hydrochloride
desyphed hydrochloride
desoxedrine
d-n,.alpha.-dimethylphenethylamine hydrochloride
des-oxa-d
wln: 1my1r &gh
(+)-methaphetamine hydrochloride
desamine
phenethylamine,.alpha.-dimethyl-, hydrochloride, (s)-(+)-
(+)-n-methylamphetamine hydrochloride
benzeneethanamine,.alpha.-dimethyl-, hydrochloride, (s)-
detrex
efroxine hydrochloride
(+)-methaphetamine chloride
nsc169506
d,l-methamphetamine hcl
n-methyl-1-phenylpropan-2-amine hydrochloride
MLS002320675
smr001338821
300-42-5
cas-300-42-5
dtxcid305544
tox21_112857
dtxsid3048865 ,
24gnz56d62 ,
n-methyl-beta-phenylisopropylaminhydrochlorid
unii-24gnz56d62
dl-methamphetimine hydrochloride
(+/-)-methamphetamine hydrochloride
2-methylamino-1-phenylpropane hydrochloride
methamphetamine hydrochloride, dl-
benzeneethanamine, n,.alpha.-dimethyl-, hydrochloride
phenethylamine, n,.alpha.-dimethyl-, hydrochloride
(dl)-methamphetamine hydrochloride
benzeneethanamine, n,.alpha.-dimethyl-, hydrochloride (1:1)
metamfetamine hydrochloride, dl-
(+/-)-n-methylamphetamine hydrochloride
n,.alpha.-dimethylphenethylamine hydrochloride
SCHEMBL42098
rac-methamphetamine hydrochloride
benzeneethanamine, n,a-dimethyl-, hydrochloride
n-methyl-1-phenylpropan-2-amine;hydrochloride
(+/-)-methamphetamine (hydrochloride) (crm)
Q27253854
methyl(1-phenylpropan-2-yl)amine hydrochloride
d,l-methamphetamine.hcl, 1mg/ml in methanol
d,l-methamphetamine.hcl

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
"The ATP-binding cassette transporter P-glycoprotein (P-gp) is known to limit both brain penetration and oral bioavailability of many chemotherapy drugs."( A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Ambudkar, SV; Brimacombe, KR; Chen, L; Gottesman, MM; Guha, R; Hall, MD; Klumpp-Thomas, C; Lee, OW; Lee, TD; Lusvarghi, S; Robey, RW; Shen, M; Tebase, BG, 2019
)
0.51
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (16)

Assay IDTitleYearJournalArticle
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID1346987P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1346986P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1296008Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening2020SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's2 (28.57)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.29

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.29 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.37 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.29)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]