Page last updated: 2024-08-01 10:07:44

onopordopicrin

Description

onopordopicrin: structure given in first source; isolated from Centaurea sonchifolia; RN given is for (3aR-(3aR*,4S*,6E,10Z,11aR*))-isomer [MeSH]

Cross-References

ID SourceID
PubMed CID12313742
MeSH IDM0203388

Synonyms (2)

Synonym
onopordopicrin
[(3as,4r,6z,10z,11ar)-10-(hydroxymethyl)-6-methyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] 2-(hydroxymethyl)prop-2-enoate

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's7 (70.00)24.3611
2020's1 (10.00)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
bethanecholcarbamate ester;
quaternary ammonium ion
muscarinic agonist2012201212.0low000010
indomethacinaromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole
analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
2012201212.0low000010
ethylmaleimidemaleimidesanticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor
2012201212.0low000010
glucose, (beta-d)-isomerD-glucopyranoseepitope;
mouse metabolite
2000200024.0low001000
arctiinglycoside;
lignan
2000200024.0low001000
sesquiterpenes1992202112.5high002071
gastrins2012201212.0low000010
germacranolide2012201212.0low000010
cnicin2011201511.0high000020
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020