onitin: from Onychium siliculosum; structure given in first source; RN from Chem Abst Index Guide 1985; RN not in Chemline 9/85 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Onychium | genus | [no description available] | Pteridaceae | A plant family of the order Polypodiales, class Filicopsida, division Pteridophyta (FERNS).[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 3085044 |
| CHEMBL ID | 261243 |
| CHEBI ID | 196151 |
| SCHEMBL ID | 16489156 |
| MeSH ID | M0133967 |
| Synonym |
|---|
| onitin |
| CHEMBL261243 |
| 4-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetramethyl-3h-inden-1-one |
| CHEBI:196151 |
| 1h-inden-1-one, 2,3-dihydro-4-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetramethyl- |
| 4-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetramethyl-3-dihydro-1h-inden-1-one |
| 53823-02-2 |
| AKOS022663882 |
| SCHEMBL16489156 |
| DTXSID20202105 |
| 4-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetramethylindanone |
| FS-9991 |
| 2,3-dihydro-4-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetramethyl-1h-inden-1-one; 2,2,5,7-tetramethyl-4-hydroxy-6-(2-hydroxyethyl)indanone |
| B0005-123296 |
| Class | Description |
|---|---|
| indanones | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID326588 | Inhibition of CaCl2-induced contraction in potassium depolarized-guinea pig ileal smooth muscle | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1 | Synthesis and pharmacological activity of aminoindanone dimers and related compounds. |
| AID1354669 | Inhibition of BACE1 (unknown origin) at 40 uM using BACE1 substrate measured after 2 hrs by FRET assay relative to control | 2018 | Journal of natural products, 06-22, Volume: 81, Issue:6 | Protoilludane, Illudalane, and Botryane Sesquiterpenoids from the Endophytic Fungus Phomopsis sp. TJ507A. |
| AID1354671 | Cytotoxicity against human L02 cells assessed as effect on cell viability at 40 uM after 24 hrs by MTT assay | 2018 | Journal of natural products, 06-22, Volume: 81, Issue:6 | Protoilludane, Illudalane, and Botryane Sesquiterpenoids from the Endophytic Fungus Phomopsis sp. TJ507A. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (29.98) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||