Page last updated: 2024-11-13

odorine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID23242585
CHEMBL ID521297
MeSH IDM0421149

Synonyms (13)

Synonym
smr001397074
odorine
MLS002472967
CHEMBL521297
NCGC00247460-01
HMS2198I12
(s)-n-[(r)-1-cinnamoylpyrrolidin-2-yl]-2-methylbutanamide
FS-8995
CS-0023383
HY-N3155
DTXSID001127316
(2s)-2-methyl-n-[(2r)-1-[(2e)-1-oxo-3-phenyl-2-propen-1-yl]-2-pyrrolidinyl]butanamide
AKOS040762138
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (5)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
USP1 protein, partialHomo sapiens (human)Potency112.20200.031637.5844354.8130AID743255
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency39.81070.707936.904389.1251AID504333
P53Homo sapiens (human)Potency35.48130.07319.685831.6228AID504706
chromobox protein homolog 1Homo sapiens (human)Potency100.00000.006026.168889.1251AID540317
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency100.00000.050127.073689.1251AID588590
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (27)

Assay IDTitleYearJournalArticle
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID338221Cytotoxicity against human Col1 cells1993Journal of natural products, Apr, Volume: 56, Issue:4
Bisamides from Aglaia species: structure analysis and potential to reverse drug resistance with cultured cells.
AID338219Cytotoxicity against human LUC1 cells1993Journal of natural products, Apr, Volume: 56, Issue:4
Bisamides from Aglaia species: structure analysis and potential to reverse drug resistance with cultured cells.
AID338220Cytotoxicity against human SK-MEL-2 cells1993Journal of natural products, Apr, Volume: 56, Issue:4
Bisamides from Aglaia species: structure analysis and potential to reverse drug resistance with cultured cells.
AID338225Cytotoxicity against human A431 cells1993Journal of natural products, Apr, Volume: 56, Issue:4
Bisamides from Aglaia species: structure analysis and potential to reverse drug resistance with cultured cells.
AID338224Cytotoxicity against vinblastine-resistant human KBV1 cells by dose-response study in presence of 1 ug/ml vinblastine1993Journal of natural products, Apr, Volume: 56, Issue:4
Bisamides from Aglaia species: structure analysis and potential to reverse drug resistance with cultured cells.
AID338222Cytotoxicity against human KB cells1993Journal of natural products, Apr, Volume: 56, Issue:4
Bisamides from Aglaia species: structure analysis and potential to reverse drug resistance with cultured cells.
AID338226Cytotoxicity against human LNCAP cells1993Journal of natural products, Apr, Volume: 56, Issue:4
Bisamides from Aglaia species: structure analysis and potential to reverse drug resistance with cultured cells.
AID338223Cytotoxicity against vinblastine-resistant human KBV1 cells1993Journal of natural products, Apr, Volume: 56, Issue:4
Bisamides from Aglaia species: structure analysis and potential to reverse drug resistance with cultured cells.
AID338227Cytotoxicity against human ZR-75-1 cells1993Journal of natural products, Apr, Volume: 56, Issue:4
Bisamides from Aglaia species: structure analysis and potential to reverse drug resistance with cultured cells.
AID338217Cytotoxicity against human BCA1 cells1993Journal of natural products, Apr, Volume: 56, Issue:4
Bisamides from Aglaia species: structure analysis and potential to reverse drug resistance with cultured cells.
AID338218Cytotoxicity against human HT1080 cells1993Journal of natural products, Apr, Volume: 56, Issue:4
Bisamides from Aglaia species: structure analysis and potential to reverse drug resistance with cultured cells.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's2 (28.57)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 20.34

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index20.34 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.78 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (20.34)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]