Compounds > octyltrichlorosilane
Page last updated: 2024-12-06

octyltrichlorosilane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Octyltrichlorosilane (OTCS) is an organosilicon compound with the formula CH3(CH2)7SiCl3. It is a colorless liquid that is used as a coupling agent in the synthesis of silicone polymers. OTCS is also used in the production of other organosilicon compounds, such as silanes and siloxanes. The synthesis of OTCS typically involves the reaction of octyl chloride with silicon tetrachloride in the presence of a catalyst, such as aluminum chloride. The reaction is typically carried out at high temperatures and pressures. OTCS is a reactive compound that can be hydrolyzed by water to form silanol groups. These silanol groups can then react with other silanol groups or other functional groups to form silicone polymers. The properties and reactivity of OTCS make it a valuable reagent for the synthesis of a wide range of silicone materials. Research on OTCS is ongoing to develop new and improved methods for its synthesis and to explore its potential applications in various fields, such as materials science, electronics, and medicine.'

Cross-References

ID SourceID
PubMed CID21354
CHEMBL ID2133549
SCHEMBL ID132734
SCHEMBL ID3177967
MeSH IDM0084396

Synonyms (33)

Synonym
octyltrichlorosilane
trichloro(octyl)silane
trichloro(octyl)silane, 97%
NCGC00164352-01
5283-66-9
silane, trichlorooctyl-
hsdb 1998
einecs 226-112-1
trichlorooctylsilane
un1801
trichloro-n-octylsilane
n-octyltrichlorosilane
O0168
AKOS016012912
unii-jv18i1wcu8
jv18i1wcu8 ,
ec 226-112-1
octyltrichlorosilane [un1801] [corrosive]
S12750
ls 2190
trichlorooctylsilane [hsdb]
SCHEMBL132734
SCHEMBL3177967
CHEMBL2133549
un 1801
silane, octyltrichloro-
co9830
DTXSID5029269
mfcd00000488
FS-4553
Q27281708
D91823
EN300-7864152

Research Excerpts

Treatment

ExcerptReferenceRelevance
"Octyltrichlorosilane-treated surfaces were functionalized with this polypeptide by spin coating and photocrosslinking."( Artificial polypeptide scaffold for protein immobilization.
Diehl, MR; Tirrell, DA; Zhang, K, 2005)		1.05
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (1)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency38.57080.000627.21521,122.0200AID651741
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's3 (37.50)24.3611
2020's1 (12.50)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 27.91

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index27.91 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.42 (4.65)
Search Engine Demand Index27.81 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (27.91)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
lauric acid
dodecanoic acid : A straight-chain, twelve-carbon medium-chain saturated fatty acid with strong bactericidal properties; the main fatty acid in coconut oil and palm kernel oil.		2.0710medium-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
antibacterial agent;
plant metabolite
stearic acid
octadecanoic acid : A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.		2.110long-chain fatty acid;
saturated fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
human metabolite;
plant metabolite
thiophenes
Thiophenes: A monocyclic heteroarene furan in which the oxygen atom is replaced by a sulfur.. thiophenes : Compounds containing at least one thiophene ring.		2.0310mancude organic heteromonocyclic parent;
monocyclic heteroarene;
thiophenes;
volatile organic compound		non-polar solvent
pentacene
[no description available]		2.0610acene;
pentacenes
sodium hydroxide
Sodium Hydroxide: A highly caustic substance that is used to neutralize acids and make sodium salts. (From Merck Index, 11th ed)		2.0710alkali metal hydroxide
perfluoro-n-nonanoic acid
perfluorononanoic acid : A fluoroalkanoic acid that is nonanoic acid in which all of the hydrogens in the alkyl chain are replaced by fluorines.		2.2510fluoroalkanoic acidpersistent organic pollutant;
surfactant;
xenobiotic
4-cyano-4'-pentylbiphenyl
[no description available]		2.4920
silicon
Silicon: A trace element that constitutes about 27.6% of the earth's crust in the form of SILICON DIOXIDE. It does not occur free in nature. Silicon has the atomic symbol Si, atomic number 14, and atomic weight [28.084; 28.086].		1.9510carbon group element atom;
metalloid atom;
nonmetal atom
aluminum oxide
Aluminum Oxide: An oxide of aluminum, occurring in nature as various minerals such as bauxite, corundum, etc. It is used as an adsorbent, desiccating agent, and catalyst, and in the manufacture of dental cements and refractories.		2.0610
ConditionIndicatedRelationship StrengthStudiesTrials