Compounds > niphimycin
Page last updated: 2024-11-13

niphimycin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

niphimycin: RN's in Chemline for cpds of unknown MF's; niphimycin A1: 56645-56-8; niphimycin A2: 56644-96-3; niphimycin B1: 56645-55-7; niphimycin B2: 56645-54-6 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID44409344
CHEMBL ID413402
MeSH IDM0056019

Synonyms (5)

Synonym
niphimycin
CHEMBL413402
12676-71-0
Q15425775
DTXSID901028155
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (10)

Assay IDTitleYearJournalArticle
AID262217ROS production in Saccharomyces cerevisiae cells at lethal concentration2006Bioorganic & medicinal chemistry letters, Mar-15, Volume: 16, Issue:6
Structure-activity relationship studies on niphimycin, a guanidylpolyol macrolide antibiotic. Part 1: The role of the N-methyl-N''-alkylguanidinium moiety.
AID262211Antifungal activity against Mucor mucedo IFO 76842006Bioorganic & medicinal chemistry letters, Mar-15, Volume: 16, Issue:6
Structure-activity relationship studies on niphimycin, a guanidylpolyol macrolide antibiotic. Part 1: The role of the N-methyl-N''-alkylguanidinium moiety.
AID262209Antimicrobial activity against Rhodotorula mucilaginosa IFO 00012006Bioorganic & medicinal chemistry letters, Mar-15, Volume: 16, Issue:6
Structure-activity relationship studies on niphimycin, a guanidylpolyol macrolide antibiotic. Part 1: The role of the N-methyl-N''-alkylguanidinium moiety.
AID262212Antifungal activity against Penicillium chrysogenum IFO 46262006Bioorganic & medicinal chemistry letters, Mar-15, Volume: 16, Issue:6
Structure-activity relationship studies on niphimycin, a guanidylpolyol macrolide antibiotic. Part 1: The role of the N-methyl-N''-alkylguanidinium moiety.
AID262215Antibacterial activity against Bacillus subtilis IFO 30072006Bioorganic & medicinal chemistry letters, Mar-15, Volume: 16, Issue:6
Structure-activity relationship studies on niphimycin, a guanidylpolyol macrolide antibiotic. Part 1: The role of the N-methyl-N''-alkylguanidinium moiety.
AID262210Antifungal activity against Aspergillus niger ATCC 62752006Bioorganic & medicinal chemistry letters, Mar-15, Volume: 16, Issue:6
Structure-activity relationship studies on niphimycin, a guanidylpolyol macrolide antibiotic. Part 1: The role of the N-methyl-N''-alkylguanidinium moiety.
AID262208Antimicrobial activity against Candida albicans IFO 10612006Bioorganic & medicinal chemistry letters, Mar-15, Volume: 16, Issue:6
Structure-activity relationship studies on niphimycin, a guanidylpolyol macrolide antibiotic. Part 1: The role of the N-methyl-N''-alkylguanidinium moiety.
AID262206Antimicrobial activity against Schizosaccharomyces pombe L972 h-2006Bioorganic & medicinal chemistry letters, Mar-15, Volume: 16, Issue:6
Structure-activity relationship studies on niphimycin, a guanidylpolyol macrolide antibiotic. Part 1: The role of the N-methyl-N''-alkylguanidinium moiety.
AID262203Antimicrobial activity against Saccharomyces cerevisiae X2180 1A2006Bioorganic & medicinal chemistry letters, Mar-15, Volume: 16, Issue:6
Structure-activity relationship studies on niphimycin, a guanidylpolyol macrolide antibiotic. Part 1: The role of the N-methyl-N''-alkylguanidinium moiety.
AID262213Antifungal activity against Rhizopus oryzae IFO 47662006Bioorganic & medicinal chemistry letters, Mar-15, Volume: 16, Issue:6
Structure-activity relationship studies on niphimycin, a guanidylpolyol macrolide antibiotic. Part 1: The role of the N-methyl-N''-alkylguanidinium moiety.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.82

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.82 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index5.12 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.82)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
nigericin
Nigericin: A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed). nigericin : A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus.		6.9710polycyclic etherantibacterial agent;
antimicrobial agent;
bacterial metabolite;
potassium ionophore
ergosterol
[no description available]		2.06103beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols		fungal metabolite;
Saccharomyces cerevisiae metabolite
amphotericin b
Amphotericin B: Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.. amphotericin B : A macrolide antibiotic used to treat potentially life-threatening fungal infections.		2.4520antibiotic antifungal drug;
macrolide antibiotic;
polyene antibiotic		antiamoebic agent;
antiprotozoal drug;
bacterial metabolite
elaiophylin
[no description available]		6.9710lactol;
macrodiolide;
monosaccharide derivative		antifungal agent;
autophagy inhibitor;
bacterial metabolite
azalomycin-f
azalomycin-F: a macrocyclic lactone antibiotic		2.4420
phosphatidylcholines
Phosphatidylcholines: Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.		2.03101,2-diacyl-sn-glycero-3-phosphocholine
ConditionIndicatedRelationship StrengthStudiesTrials