nestosyl ointment profile

Nestosyl ointment: if Belgian preparation is used add BENZOCAINE to data form; if Dutch preparation is used add Pramocaine to data form; for treatment of eczema; each gram Belgian ointment contains benzocaine 20mg, butyl aminobenzoate 20mg, resorcinol 20mg, 8-hydroxyquinoline 0.06mg & zinc oxide 100mg; Dutch ointment contains pramocaine as local anesthetic agent instead of benzocaine & butyl aminobenzoate [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	174203
MeSH ID	M0096758

Synonym
nestosyl ointment
80127-69-1
dutch nestosyl ointment
belgian nestosyl ointment
benzoic acid, 4-amino-, butyl ester, mixt. with 1,3-benzenediol, ethyl 4-aminobenzoate, 8-quinolinol and zinc oxide (zno)
zinc;benzene-1,3-diol;butyl 4-aminobenzoate;ethyl 4-aminobenzoate;oxygen(2-);quinolin-8-ol

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	6 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	6 (100.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	0 (0.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
oxyquinoline Oxyquinoline: An antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics.. quinolin-8-ol : A monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes.	3.21	6	monohydroxyquinoline	antibacterial agent; antifungal agrochemical; antiseptic drug; iron chelator
benzocaine Benzocaine: A surface anesthetic that acts by preventing transmission of impulses along NERVE FIBERS and at NERVE ENDINGS.. dextran sulfate sodium : An organic sodium salt of dextran sulfate. It induces colitis in mice.. benzocaine : A benzoate ester having 4-aminobenzoic acid as the acid component and ethanol as the alcohol component. A surface anaesthetic, it is used to suppress the gag reflex, and as a lubricant and topical anaesthetic on the larynx, mouth, nasal cavity, respiratory tract, oesophagus, rectum, urinary tract, and vagina.	2.88	4	benzoate ester; substituted aniline	allergen; antipruritic drug; sensitiser; topical anaesthetic
pramoxine pramoxine: RN given refers to parent cpd; structure. pramocaine : A member of the class of morpholines that is morpholine substituted at the nitrogen atom by a 3-(4-butoxyphenoxy)propyl group.	1.96	1	aromatic ether; morpholines	local anaesthetic
resorcinol resorcinol: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7951. resorcinol : A benzenediol that is benzene dihydroxylated at positions 1 and 3.	1.96	1	benzenediol; phenolic donor; resorcinols	erythropoietin inhibitor; sensitiser
chiniofon Hydroxyquinolines: The 8-hydroxy derivatives inhibit various enzymes and their halogenated derivatives, though neurotoxic, are used as topical anti-infective agents, among other uses.	3.21	6

Condition	Relationship Strength	Studies
Dermatitis Medicamentosa [description not available]	1.96	1
Contact Dermatitis [description not available]	2.36	2
Dermatitis, Contact A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.	2.36	2
Hand Dermatosis [description not available]	1.96	1
Hand Dermatoses Skin diseases involving the HANDS.	1.96	1
Cyanosis A bluish or purplish discoloration of the skin and mucous membranes due to an increase in the amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule.	1.97	1
Methemoglobinemia The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)	2.88	4
Anemia, Hemolytic, Acquired [description not available]	1.96	1
Acute Disease Disease having a short and relatively severe course.	1.96	1
Anemia, Hemolytic A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).	1.96	1

nestosyl ointment

Description

Cross-References

Synonyms (6)

Research

Studies (6)

Market Indicators

Research Demand Index: 17.69

Study Types