Compounds > n-propyl 2-pyridyl disulfide
Page last updated: 2024-12-08

n-propyl 2-pyridyl disulfide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID194112
CHEMBL ID4788268
SCHEMBL ID423720
MeSH IDM0066874

Synonyms (6)

Synonym
n-propyl 2-pyridyl disulfide
60681-90-5
pyridine, 2-(propyldithio)-
SCHEMBL423720
DTXSID20209497
CHEMBL4788268
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (16)

Assay IDTitleYearJournalArticle
AID1714679Antibacterial activity against Staphylococcus epidermidis ATCC 14990 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
AID1714665Antibacterial activity against multidrug-resistant Klebsiella pneumoniae ATCC 700603 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
AID1714675Antibacterial activity against hospital acquired methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
AID1714676Antibacterial activity against heterogeneous vancomycin-intermediate resistant Staphylococcus aureus Mu3 ATCC 700698 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
AID1714670Antibacterial activity against Bacillus anthracis Sterne 34F2 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
AID1714672Antibacterial activity against vancomycin-susceptible Enterococcus faecalis ATCC 29212 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
AID1714678Antibacterial activity against vancomycin-resistant Staphylococcus aureus HIP11714 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
AID1714666Antibacterial activity against Enterobacter cloacae ATCC 23355 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
AID1714681Antibacterial activity against Pseudomonas aeruginosa ATCC 15422 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
AID1714673Antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 25923 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
AID1714667Antibacterial activity against beta-lactam resistant Escherichia coli BAA 2326 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
AID1714677Antibacterial activity against vancomycin-intermediate resistant Staphylococcus aureus Mu50 ATCC 700699 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
AID1714668Antibacterial activity against multidrug-resistant Acinetobacter baumannii BAA 1605 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
AID1714680Antibacterial activity against Acinetobacter baumannii ATCC 19606 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
AID1714674Antibacterial activity against community acquired methicillin-resistant Staphylococcus aureus BAA 1747 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
AID1714671Antibacterial activity against vancomycin-resistant Enterococcus faecium ATCC 700221 assessed as zone of inhibition by disc diffusion method2018European journal of medicinal chemistry, Jan-01, Volume: 143Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (80.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.53

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.53 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.53)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
2,2'-dipyridyl
2,2'-Dipyridyl: A reagent used for the determination of iron.. 2,2'-bipyridine : A bipyridine in which the two pyridine moieties are linked by a bond between positions C-2 and C-2'.		2.3720bipyridinechelator;
ferroptosis inhibitor
triclosan
[no description available]		2.1710aromatic ether;
dichlorobenzene;
monochlorobenzenes;
phenols		antibacterial agent;
antimalarial;
drug allergen;
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
fungicide;
persistent organic pollutant;
xenobiotic
phenylalanine
Phenylalanine: An essential aromatic amino acid that is a precursor of MELANIN; DOPAMINE; noradrenalin (NOREPINEPHRINE), and THYROXINE.. L-phenylalanine : The L-enantiomer of phenylalanine.. phenylalanine : An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group.		1.9710amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
phenylalanine;
proteinogenic amino acid		algal metabolite;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
Escherichia coli metabolite;
human xenobiotic metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
benzoxazoles
1,3-benzoxazole : A benzoxazole in which the benzene ring is fused to a 1,3-oxazole ring across positions 4 and 5.. benzoxazole : Compounds based on a fused 1,2- or 1,3-oxazole and benzene bicyclic ring skeleton.		2.36201,3-benzoxazoles;
mancude organic heterobicyclic parent
vancomycin
Vancomycin: Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.. vancomycin : A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.		2.1710glycopeptideantibacterial drug;
antimicrobial agent;
bacterial metabolite
4-chloro-7-nitrobenzofurazan
4-Chloro-7-nitrobenzofurazan: A benzofuran derivative used as a protein reagent since the terminal N-NBD-protein conjugate possesses interesting fluorescence and spectral properties. It has also been used as a covalent inhibitor of both beef heart mitochondrial ATPase and bacterial ATPase.. 4-chloro-7-nitrobenzofurazan : A benzoxadiazole that is 2,1,3-benzoxadiazole which is substituted at position 4 by chlorine and at position 7 by a nitro group.		1.9610benzoxadiazole;
C-nitro compound;
organochlorine compound		EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.6.1.3 (adenosinetriphosphatase) inhibitor;
fluorescent probe;
fluorochrome
2,2'-dipyridyl disulfide
2,2'-dipyridyl disulfide: disulfide is an important moiety in this cpd. aldrithiol : A member of the class of pyridines that is pyridine which is substituted by a pyridin-2-yldisulfanediyl group at position 2. It is a reagent used in molecular biology as an oxidizing agent. Also used in peptide synthesis and for detecting thiols.		1.9710organic disulfide;
pyridines		oxidising agent
methyl 2-pyridyl disulfide
methyl 2-pyridyl disulfide: structure given in first source		2.1710
ConditionIndicatedRelationship StrengthStudiesTrials