Page last updated: 2024-12-11

n-palmitoylgalactosylsphingosine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

N-(hexadecanoyl)-beta-D-galactosylsphingosine : A D-galactosyl-N-acylsphingosine in which the ceramide N-acyl group is specified as hexadecanoyl. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID11542139
CHEBI ID83259
MeSH IDM0102206

Synonyms (19)

Synonym
n-palmitoylgalactosylsphingosine
34324-89-5
n-palmitoylpsychosine
CHEBI:83259
n-(hexadecanoyl)-1-beta-galactosyl-sphing-4-enine
beta-d-galactosyl-n-hexadecanoylsphingosine
n-(palmitoyl)-beta-d-galactosylsphingosine
n-hexadecanoyl-beta-d-galactosyl-sphing-4-enine
n-(hexadecanoyl)-beta-d-galactosylsphingosine
n-[(2s,3r,4e)-1-(beta-d-galactopyranosyloxy)-3-hydroxyoctadec-4-en-2-yl]hexadecanamide
beta-d-galactosyl-n-palmitoylsphingosine
n-[(e,2s,3r)-3-hydroxy-1-[(2r,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadec-4-en-2-yl]hexadecanamide
hexadecanamide, n-[(1s,2r,3e)-1-[(beta-d-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-
n-palmitoyl cerebroside
Q27105092
hexadecanamide,n-[(1s,2r,3e)-1-[(beta-d-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-
DTXSID901120367
n-[(1s,2r,3e)-1-[(beta-d-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]hexadecanamide
c16 galactosylceramide (d18:1/16:0)

Research Excerpts

Toxicity

ExcerptReferenceRelevance
"After 6 months, the EYEMATE-SC sensor was safe and well tolerated, and allowed continual IOP monitoring."( Safety and performance of a suprachoroidal sensor for telemetric measurement of intraocular pressure in the EYEMATE-SC trial.
Dick, HB; Hoffmann, EM; Mackert, M; Mansouri, K; Mermoud, A; Rao, HL; Seuthe, AM; Szurman, P; Weinreb, RN, 2023
)
0.91
"Device position and adverse events."( EYEMATE-SC Trial: Twelve-Month Safety, Performance, and Accuracy of a Suprachoroidal Sensor for Telemetric Measurement of Intraocular Pressure.
Dick, HB; Gillmann, K; Hoffmann, EM; Mackert, MJ; Mansouri, K; Mermoud, A; Rao, HL; Seuthe, AM; Szurman, P; Weinreb, RN, 2023
)
0.91
"The EYEMATE-SC sensor was safe and well tolerated through 12 months."( EYEMATE-SC Trial: Twelve-Month Safety, Performance, and Accuracy of a Suprachoroidal Sensor for Telemetric Measurement of Intraocular Pressure.
Dick, HB; Gillmann, K; Hoffmann, EM; Mackert, MJ; Mansouri, K; Mermoud, A; Rao, HL; Seuthe, AM; Szurman, P; Weinreb, RN, 2023
)
0.91
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
mouse metaboliteAny mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
N-acyl-beta-D-galactosylsphingosineAn N-acyl-D-galactosylsphingosine in which the anomeric configuration of the galactosyl residue is beta; sphingosine substituted at the O-1 position by a beta-D-galactosyl group and at the N-2 position by an acyl group.
HexCer(d18:1/16:0)A cerebroside in which the ceramide N-acyl group is specified as hexadecanoyl.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (46.15)18.7374
1990's3 (23.08)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's3 (23.08)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (7.69%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other12 (92.31%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]