Page last updated: 2024-12-08

n-n-propyl-n-n-butyl-beta-dopamine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

N-n-propyl-N-n-butyl-beta-dopamine: RN given refers to parent cpd; dopamine D2 receptor agonist [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID156067
CHEMBL ID351484
SCHEMBL ID6674754
MeSH IDM0065831

Synonyms (10)

Synonym
propylbutyldopamine
4-[2-[butyl(propyl)amino]ethyl]benzene-1,2-diol
CHEMBL351484
n-n-propyl-n-n-butyl-beta-(3,4-dihydroxyphenyl)ethylamine
n-pbda
1,2-benzenediol, 4-(2-(butylpropylamino)ethyl)-
n-n-propyl-n-n-butyl-beta-dopamine
71800-28-7
DTXSID90222057
SCHEMBL6674754

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" On the basis of dosage used, the positive inotropic effects of fenoldopam and propylbutyldopamine were much weaker than dopamine."( Effects of dopamine D1 and dopamine D2 receptor agonists on coronary and peripheral hemodynamics.
Abel, FL; Fennell, WH; Zhao, RR, 1990
)
0.28
"L-1) shifted the dose-response curves to the right in a nonparallel fashion and decreased the maximal response (Emax) of both the fenoldopam(FODA, a selective DA1 agonist)-induced and the propyl-buty-dopamine(PBDA, a selective DA2 agonist)-induced vasorelaxation showing a non-competitive antagonistic action."( [Effects of l-stepholidine on the peripheral vascular dopamine DA1 and DA2 receptor subtypes].
Guo, W; Jin, G; Zhang, W; Zhao, R; Zhi, J, 1998
)
0.3
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID167290Inhibition of the constrictor response to electrical stimulation in rabbit ear artery.1986Journal of medicinal chemistry, May, Volume: 29, Issue:5
Dopamine receptor agonists: 3-allyl-6-chloro-2,3,4,5-tetrahydro- 1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol and a series of related 3-benzazepines.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19907 (53.85)18.7374
1990's5 (38.46)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.48

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.48 (24.57)
Research Supply Index2.94 (2.92)
Research Growth Index4.42 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.48)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (5.88%)5.53%
Reviews2 (11.76%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other14 (82.35%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]