Page last updated: 2024-12-06

n,n-dimethylhydroxylamine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

N,N-dimethylhydroxylamine (DMH) is a colorless liquid with a pungent odor. It is a versatile reagent used in various chemical reactions, including as a reducing agent and a catalyst. DMH can be synthesized through several methods, including the reaction of dimethylamine with hydrogen peroxide or by the reduction of nitrosodimethylamine. It is a strong reducing agent and is often used in the synthesis of other compounds, particularly those containing N-N bonds. DMH exhibits various pharmacological activities, including anti-inflammatory and antioxidant effects. It has also been investigated as a potential therapeutic agent for various conditions, including cancer and diabetes. The unique properties of DMH, particularly its reducing ability and its ability to stabilize free radicals, make it an important compound in the field of chemistry and medicine.'

N,N-dimethylhydroxylamine: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID27970
MeSH IDM0174633

Synonyms (17)

Synonym
n,n-dimethylhydroxylamine
methanamine, n-hydroxy-n-methyl-
AKOS006228086
5725-96-2
m0dv42c08k ,
unii-m0dv42c08k
dimethylhydroxylamine
dimethyl hydroxylamine
dimethyl-hydroxylamine
n,n-dimethyl-hydroxylamine
DTXSID5063990
[hydroxy(methyl)amino]methane #
dimethylamine n-oxide
n,n-dimethylamine oxide
n-hydroxy-n-methylmethanamine
Q24004551
dimethylhydroxyl-amine

Research Excerpts

Toxicity

ExcerptReferenceRelevance
"The toxic potency of three industrially used hydroxylamines was studied in human blood cells in vitro."( Two mechanisms for toxic effects of hydroxylamines in human erythrocytes: involvement of free radicals and risk of potentiation.
Baars, LG; Bisschops, RA; Evelo, CT; Neis, JM; Spooren, AA, 1998
)
0.3
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.38

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.38 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.38)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]