Assay ID | Title | Year | Journal | Article |
AID647904 | Selectivity ratio of IC50 for african green monkey Vero cells to IC50 for Leishmania donovani S1 promastigotes | 2012 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 22, Issue:4
| Synthesis and antikinetoplastid activity of a series of N,N'-substituted diamines. |
AID1348961 | Antimalarial activity against chloroquine-resistant Plasmodium falciparum W2 after 48 hrs by LDH release assay | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | A minimalistic approach to develop new anti-apicomplexa polyamines analogs. |
AID1055494 | Cytotoxicity against human HuH7 cells | 2013 | European journal of medicinal chemistry, , Volume: 70 | Synthesis and evaluation of hexahydropyrimidines and diamines as novel hepatitis C virus inhibitors. |
AID1348964 | Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 48 hrs | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | A minimalistic approach to develop new anti-apicomplexa polyamines analogs. |
AID1055493 | Selectivity index, ratio of CC50 for human HuH7 cells to EC50 for cell culture derived HCV expressing NS5A-GFP fusion protein | 2013 | European journal of medicinal chemistry, , Volume: 70 | Synthesis and evaluation of hexahydropyrimidines and diamines as novel hepatitis C virus inhibitors. |
AID647901 | Cytotoxicity against african green monkey Vero cells at 4.76 ug/ml after 48 hrs by neutral red assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 22, Issue:4
| Synthesis and antikinetoplastid activity of a series of N,N'-substituted diamines. |
AID647903 | Selectivity ratio of IC50 for african green monkey Vero cells to IC50 for Trypanosoma brucei MITat 427 clone 221a trypomastigotes | 2012 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 22, Issue:4
| Synthesis and antikinetoplastid activity of a series of N,N'-substituted diamines. |
AID1348962 | Selectivity index, ratio of IC50 for African green monkey Vero cells to IC50 for chloroquine-resistant Plasmodium falciparum W2 | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | A minimalistic approach to develop new anti-apicomplexa polyamines analogs. |
AID1348959 | Antimalarial activity against chloroquine-sensitive Plasmodium falciparum D6 after 48 hrs by LDH release assay | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | A minimalistic approach to develop new anti-apicomplexa polyamines analogs. |
AID647776 | Antitrypanosomal activity against Trypanosoma brucei MITat 427 clone 221a trypomastigotes after 3 days by alamar blue assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 22, Issue:4
| Synthesis and antikinetoplastid activity of a series of N,N'-substituted diamines. |
AID1348963 | Growth inhibition of GFP-fused Toxoplasma gondii RH infected in HFF at 1 uM after 3 days by fluorescence microscopic method relative to control | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | A minimalistic approach to develop new anti-apicomplexa polyamines analogs. |
AID647778 | Antileishmanial activity against Leishmania donovani S1 promastigotes after 72 hrs by alamar blue assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 22, Issue:4
| Synthesis and antikinetoplastid activity of a series of N,N'-substituted diamines. |
AID1348960 | Selectivity index, ratio of IC50 for African green monkey Vero cells to IC50 for chloroquine-sensitive Plasmodium falciparum D6 | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | A minimalistic approach to develop new anti-apicomplexa polyamines analogs. |
AID1055495 | Antiviral activity against cell culture derived HCV expressing NS5A-GFP fusion protein infected in human HuH7 cells assessed as inhibition of viral life cycle after 72 hrs by Hoechst-33342 staining-based confocal microscopy | 2013 | European journal of medicinal chemistry, , Volume: 70 | Synthesis and evaluation of hexahydropyrimidines and diamines as novel hepatitis C virus inhibitors. |
AID647777 | Antitrypanosomal activity against Trypanosoma cruzi clone CL-Brener epimastigotes after 14 days by alamar blue assay | 2012 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 22, Issue:4
| Synthesis and antikinetoplastid activity of a series of N,N'-substituted diamines. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |