N-ethyl-3-piperidyl benzilate: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 62504 |
| CHEMBL ID | 342669 |
| SCHEMBL ID | 1742170 |
| MeSH ID | M0064300 |
| Synonym |
|---|
| epb (van) |
| benzeneacetic acid, alpha-hydroxy-alpha-phenyl-, 1-ethyl-3-piperidinyl ester |
| nsc 524174 |
| brn 0309916 |
| 3-piperidinol, 1-ethyl-, benzilate (ester) |
| dea no. 7482 |
| ditran jb 318 |
| 3-piperidinol, benzilate (ester) |
| n-ethyl-3-piperidyl benzilate |
| nsc-524174 |
| benzilic acid, 1-ethyl-3-piperidyl ester |
| nsc524174 |
| 1-ethyl-3-piperidyl benzilate |
| benzeneacetic acid, 1-ethyl-3-piperidinyl ester |
| wln: t6mtj covxqr&r& c2 |
| 3567-12-2 |
| epb , |
| jb 318 |
| CHEMBL342669 , |
| (1-ethylpiperidin-3-yl) 2-hydroxy-2,2-diphenylacetate |
| 02j52696mz , |
| 4-21-00-00029 (beilstein handbook reference) |
| unii-02j52696mz |
| SCHEMBL1742170 |
| benzeneacetic acid, .alpha.-hydroxy-.alpha.-phenyl-, 1-ethyl-3-piperidinyl ester |
| OJYOTLHNSMYONM-UHFFFAOYSA-N |
| n-ethyl-3-piperidylbenzilate |
| bdbm50473046 |
| (1-ethyl-3-piperidyl) 2-hydroxy-2,2-diphenyl-acetate |
| benzeneacetic acid, alpha-hydroxy-alpha-phenyl-, 1-ethyl-3-piperidinyl ester (9ci) |
| Q6951360 |
| DTXSID20863199 |
| 1-ethyl-3-piperidinyl alpha-hydroxy-alpha-phenylbenzeneacetate |
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Ki | 0.0015 | 0.0001 | 0.5797 | 10.0000 | AID142341 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | Ki | 0.0015 | 0.0001 | 1.4833 | 9.1400 | AID142341 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | Ki | 0.0015 | 0.0001 | 0.6868 | 8.2600 | AID142341 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | Ki | 0.0015 | 0.0001 | 0.6661 | 8.2600 | AID142341 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | Ki | 0.0015 | 0.0001 | 0.5890 | 8.2600 | AID142341 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID24405 | Partition coefficient (logP) | 2000 | Journal of medicinal chemistry, Nov-16, Volume: 43, Issue:23 | Synthesis, (18)F-labeling, and biological evaluation of piperidyl and pyrrolidyl benzilates as in vivo ligands for muscarinic acetylcholine receptors. |
| AID142341 | Tested in vitro for binding affinity against Muscarinic acetylcholine receptor from rat brain using [3H]- Scopolamine as radioligand | 2000 | Journal of medicinal chemistry, Nov-16, Volume: 43, Issue:23 | Synthesis, (18)F-labeling, and biological evaluation of piperidyl and pyrrolidyl benzilates as in vivo ligands for muscarinic acetylcholine receptors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (21.72) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||