| Assay ID | Title | Year | Journal | Article |
|---|
| AID1124339 | Inactivation of cytochrome P450 in rat liver microsomes assessed as inhibition of aminopyrine demethylation at 1 mM measured without preincubation by Nash reagent based colorimetry in presence of flavoprotein amine oxidase alternate substrate-inhibitor me | 1979 | Journal of medicinal chemistry, Jul, Volume: 22, Issue:7
| Cyclopropylamines as suicide substrates for cytochromes P-450. |
| AID1124334 | Inactivation of cytochrome P450 in rat liver microsomes assessed as inhibition of aminopyrine demethylation at 1 mM measured without preincubation by Nash reagent based colorimetry (Rvb = 0%) | 1979 | Journal of medicinal chemistry, Jul, Volume: 22, Issue:7
| Cyclopropylamines as suicide substrates for cytochromes P-450. |
| AID34054 | Evaluated in vivo for inhibition of liver mitochondrial aldehyde dehydrogenase activity 2 hour after administering into rats, at a dose of 1.25 mmol/kg | 1984 | Journal of medicinal chemistry, Oct, Volume: 27, Issue:10
| Latent inhibitors of aldehyde dehydrogenase as alcohol deterrent agents. |
| AID1124340 | Inactivation of cytochrome P450 in rat liver microsomes assessed as inhibition of aminopyrine demethylation at 1 mM preincubated for 12 mins measured 5 mins after substrate addition by Nash reagent based colorimetry in presence of flavoprotein amine oxida | 1979 | Journal of medicinal chemistry, Jul, Volume: 22, Issue:7
| Cyclopropylamines as suicide substrates for cytochromes P-450. |
| AID1124336 | Inactivation of cytochrome P450 in rat liver microsomes assessed as inhibition of aminopyrine demethylation at 1 mM measured without preincubation by Nash reagent based colorimetry in presence of GSH (Rvb = 0%) | 1979 | Journal of medicinal chemistry, Jul, Volume: 22, Issue:7
| Cyclopropylamines as suicide substrates for cytochromes P-450. |
| AID1124338 | Inactivation of cytochrome P450 in rat liver microsomes assessed as inhibition of aminopyrine demethylation at 1 mM preincubated for 12 mins measured 5 mins after substrate addition by Nash reagent based colorimetry in presence of CO/O2 (80:20) (Rvb = 0%) | 1979 | Journal of medicinal chemistry, Jul, Volume: 22, Issue:7
| Cyclopropylamines as suicide substrates for cytochromes P-450. |
| AID34055 | Evaluated in vivo for inhibition of liver mitochondrial aldehyde dehydrogenase activity 2 hour after administering into 5 to 8 rats, and percentage of activity remaining was reported at a concentration of 1.25 mmol/Kg | 1984 | Journal of medicinal chemistry, Oct, Volume: 27, Issue:10
| Latent inhibitors of aldehyde dehydrogenase as alcohol deterrent agents. |
| AID1124335 | Inactivation of cytochrome P450 in rat liver microsomes assessed as inhibition of aminopyrine demethylation at 1 mM preincubated for 12 mins measured 5 mins after substrate addition by Nash reagent based colorimetry in absence of cofactor NADPH-generating | 1979 | Journal of medicinal chemistry, Jul, Volume: 22, Issue:7
| Cyclopropylamines as suicide substrates for cytochromes P-450. |
| AID1124333 | Inactivation of cytochrome P450 in rat liver microsomes assessed as inhibition of aminopyrine demethylation at 1 mM preincubated for 12 mins measured 5 mins after substrate addition by Nash reagent based colorimetry (Rvb = 0%) | 1979 | Journal of medicinal chemistry, Jul, Volume: 22, Issue:7
| Cyclopropylamines as suicide substrates for cytochromes P-450. |
| AID1124337 | Inactivation of cytochrome P450 in rat liver microsomes assessed as inhibition of aminopyrine demethylation at 1 mM preincubated for 12 mins measured 5 mins after substrate addition by Nash reagent based colorimetry in presence of GSH (Rvb = 0%) | 1979 | Journal of medicinal chemistry, Jul, Volume: 22, Issue:7
| Cyclopropylamines as suicide substrates for cytochromes P-450. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |