Assay ID | Title | Year | Journal | Article |
AID90274 | Concentration required for 50% growth inhibition of the following cell lines human burkitt lymphoma cells | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID539777 | Cytotoxicity against human J82 cells at 10 uM after 72 hrs by MTT assay | 2010 | Bioorganic & medicinal chemistry, Dec-01, Volume: 18, Issue:23
| N⁶-Alkyladenosines: Synthesis and evaluation of in vitro anticancer activity. |
AID130975 | Antitumor activity against mouse leukemia, L-1210(DBA/2 Ha Mice) % increase in life span at 3.12 mg/kg of dose per day | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID539783 | Induction of MMP9 activity in human T24 cells after 1 hr by zymography | 2010 | Bioorganic & medicinal chemistry, Dec-01, Volume: 18, Issue:23
| N⁶-Alkyladenosines: Synthesis and evaluation of in vitro anticancer activity. |
AID138630 | Antitumor activity against mouse leukemia, L-1210(DBA/2 Ha Mice) mean life span (days) of the mouse after fractionated dosage(dose divided in two halves and administered in two daily injections) at 6.25 mg/kg of dose per day | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID539779 | Cytotoxicity against human MDA-MB-231 cells at 10 uM after 72 hrs by MTT assay | 2010 | Bioorganic & medicinal chemistry, Dec-01, Volume: 18, Issue:23
| N⁶-Alkyladenosines: Synthesis and evaluation of in vitro anticancer activity. |
AID138966 | Antitumor activity against slow growing spontaneous mammary tumors in the DBA/2 Ha-DD mouse number of days reacquired fro tumor growth 3.8 mg/kg/day x 5 melphalan once in 5 days | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID539778 | Cytotoxicity against human Caco-2 cells at 10 uM after 72 hrs by MTT assay | 2010 | Bioorganic & medicinal chemistry, Dec-01, Volume: 18, Issue:23
| N⁶-Alkyladenosines: Synthesis and evaluation of in vitro anticancer activity. |
AID138631 | Antitumor activity against slow growing spontaneous mammary tumors in the DBA/2 Ha-DD mouse mean life span in days at 50 mg/kg give 5 times once in 5 days | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID139992 | Concentration required for 50% growth inhibition of the following cell lines mouse fibro blasts | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID155531 | Inhibition of Trypanosoma brucei phosphoglycerate kinase (PGK); inactive at 4 mM | 2000 | Journal of medicinal chemistry, Nov-02, Volume: 43, Issue:22
| Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine. |
AID539782 | Inhibition of human T24 cells invasion on Matrigel after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Dec-01, Volume: 18, Issue:23
| N⁶-Alkyladenosines: Synthesis and evaluation of in vitro anticancer activity. |
AID539776 | Cytotoxicity against human T24 cells at 10 uM after 72 hrs by MTT assay | 2010 | Bioorganic & medicinal chemistry, Dec-01, Volume: 18, Issue:23
| N⁶-Alkyladenosines: Synthesis and evaluation of in vitro anticancer activity. |
AID130490 | antitumor activity against mouse leukemia, L-1210(DBA/2 Ha Mice) % increase in life span at 3.12 mg/kg of dose per day | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID539781 | Growth inhibition of human T24 cells assessed as reduction of cell count after trypsinization at 10 uM after 72 hrs by MTT assay | 2010 | Bioorganic & medicinal chemistry, Dec-01, Volume: 18, Issue:23
| N⁶-Alkyladenosines: Synthesis and evaluation of in vitro anticancer activity. |
AID130977 | Antitumor activity against slow growing spontaneous mammary tumors in the DBA/2 Ha-DD mouse % increased in life span 3.8 mg/kg/day x 5 melphalan + 50 mg/kg/day compound | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID103053 | Concentration required for 50% growth inhibition of human breast tumor cells MCF-7 human breast carcinoma cells | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID25507 | HPLC capacity factor (k') | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| Dog coronary artery adenosine receptor: structure of the N6-alkyl subregion. |
AID539780 | Cytotoxicity against human T24 cells assessed as inhibition of clones formation at 10 uM after 1 week by clonogenic assay | 2010 | Bioorganic & medicinal chemistry, Dec-01, Volume: 18, Issue:23
| N⁶-Alkyladenosines: Synthesis and evaluation of in vitro anticancer activity. |
AID91137 | Concentration required for 50% growth inhibition of the following cell lines human fibro blast cells | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID201887 | Concentration required for 50% growth inhibition of the following cell lines sarcoma S-180 cells | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID130976 | Antitumor activity against slow growing spontaneous mammary tumors in the DBA/2 Ha-DD mouse % increased in life span 3.8 mg/kg/day x 5 melphalan + 50 mg/kg/day | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID539784 | Inhibition of human T24 cell migration by wound healing assay | 2010 | Bioorganic & medicinal chemistry, Dec-01, Volume: 18, Issue:23
| N⁶-Alkyladenosines: Synthesis and evaluation of in vitro anticancer activity. |
AID48652 | Concentration required for 50% growth inhibition of the following cell lines Carcinoma TA-3 cells | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID138629 | Antitumor activity against mouse leukemia, L-1210(DBA/2 Ha Mice) mean life span ( days) of the mouse after the dosage at 1.56 mg/kg of dose per day | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID228918 | Molar potency ratio was evaluated | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| Dog coronary artery adenosine receptor: structure of the N6-alkyl subregion. |
AID201700 | Concentration required for 50% growth inhibition of human breast tumor cells SW-613 human breast adenocarcinoma cells | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID1646835 | Activation of human STING expressed in monocytes co-expressing IFN assessed as alkaline phosphatase secretion by SEAP reporter gene assay | 2020 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 30, Issue:2
| Structure activity relationship, 6-modified purine riboside analogues to activate hSTING, stimulator of interferon genes. |
AID101497 | Concentration required for 50% growth inhibition of the following cell lines Leukemia L-1210 cells | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
AID89994 | Concentration required for 50% growth inhibition of the following cell lines human bladder carcinoma cells | 1980 | Journal of medicinal chemistry, Dec, Volume: 23, Issue:12
| Some short-chain N6-substituted adenosine analogues with antitumor properties. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |