Page last updated: 2024-12-07

n-acetylneuraminosyl(alpha2-6)lactosamine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine : An amino trisaccharide consisting of an N-acetyl-alpha-neuraminyl residue attached to the galactose residue of N-acetyllactosamine via an alpha-(2->6)-linkage. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID125128
CHEBI ID17725
SCHEMBL ID6277035
MeSH IDM0173923

Synonyms (33)

Synonym
alpha-n-acetylneuraminyl-2,6-beta-d-galactosyl-1,4-n-acetyl-beta-d-glucosamine
C04886
n-acetylneuraminosyl(alpha2-6)lactosamine
neuacalpha2,6galnacbeta1,4glcnac
alpha-n-acetylneuraminyl-(2->6)-beta-d-galactosyl-(1->4)-n-acetyl-beta-d-glucosamine
o-(n-acetyl-alpha-neuraminosyl)-(26)-o-beta-d-galactopyranosyl-(1->-4)-2-(acetylamino)-2-deoxy-beta-d-glucopyranose
neu5aca2-6galb1-4glcnacb
CHEBI:17725
neuacalpha2,6galbeta1,4glcnac
alpha-neunac-(2->6)-beta-d-gal-(1->4)-beta-d-glcnac
6-sialyllactosamine
5-acetamido-3,5-dideoxy-d-glycero-alpha-d-galacto-non-2-ulopyranonosyl-(2->6)-beta-d-galactopyranosyl-(1->4)-2-acetamido-2-deoxy-beta-d-glucopyranose
neuacalpha2-6galbeta1-4glcnacbeta
alpha-neupnac-(2->6)-beta-d-galp-(1->4)-beta-d-glcpnac
alpha-n-acetylneuraminyl-2,6-beta-delta-galactosyl-1,4-n-acetyl-beta-delta-glucosamine
64364-50-7
o-(n-acetyl-a-neuraminosyl)-(2->6)-o-b-d-galactopyranosyl-(1->4)-2-(acetylamino)-2-deoxy-b-d-glucopyranose
neuac-lact
(n-acetylneuraminosyl(alpha2-6)lactosamine)
o-(n-acetyl-alpha-neuraminosyl)-(2->6)-o-beta-delta-galactopyranosyl-(1->-4)-2-(acetylamino)-2-deoxy-beta-delta-glucopyranose
(2r,4s,5r,6r)-5-acetamido-2-{[(2r,3r,4s,5r,6s)-6-{[(2r,3s,4r,5r,6r)-5-acetamido-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-3,4,5-trihydroxyoxan-2-yl]methoxy}-4-hydroxy-6-[(1r,2r)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
beta-d-glucopyranose, o-(n-acetyl-alpha-neuraminosyl)-(2-6)-o-beta-d-galactopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-
4BH3
SCHEMBL6277035
(n-acetylneuraminosyl(a2-6)lactosamine)
a-n-acetylneuraminyl-2,6-b-d-galactosyl-1,4-n-acetyl-b-d-glucosamine
o-(n-acetyl-alpha-neuraminosyl)-(2->6)-o-beta-d-galactopyranosyl-(1->4)-2-(acetylamino)-2-deoxy-beta-d-glucopyranose
o-(n-acetyl-alpha-neuraminosyl)-(2->6)-o-beta-delta-galactopyranosyl-(1->4)-2-(acetylamino)-2-deoxy-beta-delta-glucopyranose
DTXSID60982914
3,5-dideoxy-5-[(1-hydroxyethylidene)amino]non-2-ulopyranonosyl-(2->6)hexopyranosyl-(1->4)-2-deoxy-2-[(1-hydroxyethylidene)amino]hexopyranose
Q27102559
(6r)-5-(acetylamino)-3,5-dideoxy-6-[(1r,2r)-1,2,3-trihydroxypropyl]-beta-l-threo-hex-2-ulopyranonosyl-(2->6)-beta-d-galactopyranosyl-(1->4)-2-(acetylamino)-2-deoxy-beta-d-glucopyranose
4u1
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
epitopeThe biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
glucosamine oligosaccharide
amino trisaccharideAn amino oligosaccharide that is a trisaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID977611Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB2013Nature, May-16, Volume: 497, Issue:7449
Receptor binding by a ferret-transmissible H5 avian influenza virus.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (17)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (5.88)18.7374
1990's7 (41.18)18.2507
2000's4 (23.53)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.43

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.43 (24.57)
Research Supply Index2.89 (2.92)
Research Growth Index5.32 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.43)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (5.88%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other16 (94.12%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]