Compounds > n-4-hydroxymethylbenzylglucamine dithiocarbamate

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n-4-hydroxymethylbenzylglucamine dithiocarbamate

Description

N-4-hydroxymethylbenzylglucamine dithiocarbamate: cadmium chelating agent; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	119597
MeSH ID	M0186619

Synonyms (9)

Synonym
n-4-hydroxymethylbenzylglucamine dithiocarbamate
[4-(hydroxymethyl)phenyl]methyl-[(2s,3r,4r,5r)-2,3,4,5,6-pentahydroxyhexyl]carbamodithioic acid
d-glucitol, 1-deoxy-1-((dithiocarboxy)((4-(hydroxymethyl)phenyl)methyl)amino)-
n-p-hydroxymethylbenzyl-d-glucamine dithiocarbamate
sodium n-p-hydroxymethylbenzyl-d-glucamine dithiocarbamate
n-hbgd
127531-17-3
1-deoxy-1-[{[4-(hydroxymethyl)phenyl]methyl}(sulfanylcarbonothioyl)amino]hexitol
DTXSID60925907

Research

Studies (9)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	8 (88.89)	18.2507
2000's	1 (11.11)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	9 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Description	Relationhip Strength	Studies	Trials	Classes	Roles
n-benzylglucamine dithiocarbamate	[no description available]	medium	9	0
ditiocarb	[no description available]	medium	2	0	dithiocarbamic acids	chelator; copper chelator
sorbitol	[no description available]	medium	9	0	glucitol	cathartic; Escherichia coli metabolite; food humectant; human metabolite; laxative; metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite; sweetening agent
cadmium	[no description available]	medium	7	0	cadmium molecular entity; zinc group element atom
acivicin	[no description available]	medium	1	0	isoxazoles; non-proteinogenic L-alpha-amino acid; organochlorine compound	antileishmanial agent; antimetabolite; antimicrobial agent; antineoplastic agent; EC 2.3.2.2 (gamma-glutamyltransferase) inhibitor; glutamine antagonist; metabolite
probenecid	[no description available]	medium	1	0	benzoic acids; sulfonamide	uricosuric drug
isoxazoles	[no description available]	medium	1	0	isoxazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
n-methyl-d-glucamine dithiocarbamate	[no description available]	medium	1	0
phloretin	[no description available]	medium	1	0	dihydrochalcones	antineoplastic agent; plant metabolite
phlorhizin	[no description available]	medium	1	0	aryl beta-D-glucoside; dihydrochalcones; monosaccharide derivative	antioxidant; plant metabolite
n-(4-methoxybenzyl)glucamine dithiocarbamate	[no description available]	medium	2	0
metallothionein	[no description available]	medium	1	0

Condition	Indicated	Relationship Strength	Studies	Trials
Acute Liver Injury, Drug-Induced	0	low	1	0
Cadmium Poisoning	0	low	1	0
Carcinoma 256, Walker	0	low	1	0
Carcinosarcoma 256, Walker	0	low	1	0
Chemical and Drug Induced Liver Injury	0	low	1	0
Chemically-Induced Liver Toxicity	0	low	1	0
Drug-Induced Acute Liver Injury	0	low	1	0
Drug-Induced Liver Disease	0	low	1	0
Drug-Induced Liver Injury	0	low	1	0
Hepatitis, Drug-Induced	0	low	1	0
Hepatitis, Toxic	0	low	1	0
Itai-Itai	0	low	1	0
Liver Diseases	0	low	1	0
Liver Dysfunction	0	low	1	0
Liver Injury, Drug-Induced	0	low	1	0
Liver Injury, Drug-Induced, Acute	0	low	1	0
Poisoning, Cadmium	0	low	1	0
Toxic Hepatitis	0	low	1	0

Research Highlights

Safety/Toxicity (3)

Article	Year
Effects of dithiocarbamates on toxicity of cadmium in rat primary hepatocyte cultures. Toxicology, Jan-15, Volume: 116, Issue: 1-3	1997
Prevention of renal toxicity of cis-diamminedichloroplatinum by dithiocarbamates in rats. Toxicology letters, Volume: 66, Issue: 2	1993
Protective effects of dithiocarbamates against renal toxicity of cis-diamminedichloroplatinum in rats. Renal failure, Volume: 16, Issue: 3	1994
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]