Page last updated: 2024-12-08

n-(phenylsulfonyl)glycine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID220662
CHEMBL ID37054
SCHEMBL ID359770
MeSH IDM0292875

Synonyms (42)

Synonym
EU-0083911
HMS1490F06
nsc121986
nsc-121986
5398-96-9
nsc-3682
nsc3682
CHEMDIV3_006100
CBDIVE_002981
OPREA1_645532
OPREA1_227014
CBCHROMO1_000178
benzenesulfonylamino-acetic acid
IDI1_024010
CHEMBL37054 ,
2-(phenylsulfonamido)acetic acid
AKOS000264084
BRD-K91605397-001-01-0
n-(phenylsulfonyl)glycine
bdbm50016561
2-(benzenesulfonamido)acetic acid
2-benzenesulfonamidoacetic acid
EN300-06046
CCG-117199
STL477593
AB01314976-02
WTSZSAHZIMPSDM-UHFFFAOYSA-N
n-benzenesulfonyl-glycine
SCHEMBL359770
[(phenylsulfonyl)amino]acetic acid, aldrichcpr
(phenylsulfonyl)glycine
n-benzenesulfonylglycine
[(phenylsulfonyl)amino]acetic acid
NCGC00320593-01
mfcd00233404
noname_454
DTXSID90901350
A870579
glycine, n-(phenylsulfonyl)-; n-(phenylsulfonyl)glycine
CS-0453500
PD180071
Z45658533
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (1)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)IC50 (µMol)132.00000.00041.877310.0000AID34970; AID381848
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (9)

Assay IDTitleYearJournalArticle
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
AID537157Inhibition of Fischer-344 rat lens ALR2 by least-square analysis2010Journal of medicinal chemistry, Nov-11, Volume: 53, Issue:21
A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity.
AID381848Inhibition of aldose reductase in rat lenses2008Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
Design and synthesis of N-(3,5-difluoro-4-hydroxyphenyl)benzenesulfonamides as aldose reductase inhibitors.
AID34970Inhibitory concentration against aldose reductase obtained from rat lens1989Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
N- and 2-substituted N-(phenylsulfonyl)glycines as inhibitors of rat lens aldose reductase.
AID537155Inhibition of Fischer-344 rat kidney AK1A1 at 100 uM2010Journal of medicinal chemistry, Nov-11, Volume: 53, Issue:21
A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity.
AID537153Inhibition of rat lens ALR22010Journal of medicinal chemistry, Nov-11, Volume: 53, Issue:21
A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity.
AID537160Selectivity ratio of inhibition of Fischer-344 rat lens ALR2sto inhibition of Fischer-344 rat kidney AK1A1 at 100 uM2010Journal of medicinal chemistry, Nov-11, Volume: 53, Issue:21
A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity.
AID537156Inhibition of Fischer-344 rat lens ALR2 at 100 uM2010Journal of medicinal chemistry, Nov-11, Volume: 53, Issue:21
A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.51

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.51 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.59 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.51)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]