Compounds > n-(3,4-dimethyl-5-isoxazolyl)-4-amino-1,2-naphthoquinone
Page last updated: 2024-11-07

n-(3,4-dimethyl-5-isoxazolyl)-4-amino-1,2-naphthoquinone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

N-(3,4-dimethyl-5-isoxazolyl)-4-amino-1,2-naphthoquinone: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID133732
CHEMBL ID2001103
SCHEMBL ID3272156
SCHEMBL ID5065021
MeSH IDM0181909

Synonyms (24)

Synonym
(4e)-4-(3,4-dimethylisoxazol-5-yl)imino-2-hydroxy-naphthalen-1-one
4-((3,4-dimethyl-5-isoxazolyl)imino)-2-hydroxy-1(4h)-naphthalenone
2-hidroxi-n-(3,4-dimetil-5-isoxazolil)-1,4-naftoquinona-4-imina
81620-91-9
1,2-naphthalenedione, 4-((3,4-dimethyl-5-isoxazolyl)amino)-
3,4-dianq
NCI60_026108
nsc673787
nsc-673787
2-hydroxy-n-(3,4-dimethyl-5-isoxazolyl)-1,4-naphthoquinone-4-imine
2-hydroxy-n-(3,4-dimethyl-5-isoxazolyl)-1,4-naphthoquinone imine
2-hydroxy-n-(3,4-dimethyl-5-isoxazolyl)-1,4-naphthoquinoneimine
brn 1005485
1(4h)-naphthalenone, 4-((3,4-dimethyl-5-isoxazolyl)imino)-2-hydroxy-
1,4-naphthoquinone imine, n-(3,4-dimethyl-5-isoxazolyl)-2-hydroxy-
2-hidroxi-n-(3,4-dimetil-5-isoxazolil)-1,4-naftoquinona-4-imina [italian]
81620-95-3
n-(3,4-dimethyl-5-isoxazolyl)-4-amino-1,2-naphthoquinone
DTXSID50231226
SCHEMBL3272156
SCHEMBL5065021
CHEMBL2001103
DTXSID001169035
2-hydroxy-n-(3,4-dimethyl-5-isoxazolyl)-1,4-naphthoquinon-4-imine
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's6 (75.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.87

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.87 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.17 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.87)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
2-naphthol
2-naphthol: RN given refers to parent cpd. 2-naphthol : A naphthol carrying a hydroxy group at position 2.. naphthols : Any hydroxynaphthalene derivative that has a single hydroxy substituent.		3.2460naphtholantinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger
potassium cyanide
[no description available]		1.9910cyanide salt;
one-carbon compound;
potassium salt		EC 1.15.1.1 (superoxide dismutase) inhibitor;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
neurotoxin
isoxazoles
Isoxazoles: Azoles with an OXYGEN and a NITROGEN next to each other at the 1,2 positions, in contrast to OXAZOLES that have nitrogens at the 1,3 positions.. isoxazole : A monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles.. isoxazoles : Oxazoles in which the N and O atoms are adjacent.		3.4980isoxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
salicylhydroxamic acid
[no description available]		1.9910hydroxamic acid;
phenols		antibacterial drug;
EC 1.11.2.2 (myeloperoxidase) inhibitor;
EC 3.5.1.5 (urease) inhibitor;
trypanocidal drug
betadex
beta-Cyclodextrins: Cyclic GLUCANS consisting of seven (7) glucopyranose units linked by 1,4-glycosidic bonds.		210cyclodextrin
naphthoquinones
Naphthoquinones: Naphthalene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.		2.6830
antimycin a
Antimycin A: An antibiotic substance produced by Streptomyces species. It inhibits mitochondrial respiration and may deplete cellular levels of ATP. Antimycin A1 has been used as a fungicide, insecticide, and miticide. (From Merck Index, 12th ed). antimycin A : A nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by Streptomyces bacteria and has found commercial use as a fish poison.		1.9910amidobenzoic acid
nad
NAD(1-) : An anionic form of nicotinamide adenine dinucleotide arising from deprotonation of the two OH groups of the diphosphate moiety.		1.9910organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Infections, Staphylococcal
[description not available]		01.9810
Staphylococcal Infections
Infections with bacteria of the genus STAPHYLOCOCCUS.		01.9810
Bacterial Disease
[description not available]		01.9810
Bacterial Infections
Infections by bacteria, general or unspecified.		01.9810