n-(2-hydroxyethyl)ethylenediamine, also known as hydroxyethyl ethylenediamine (HEEDA), is a chelating agent used in a variety of applications, including metal plating, metal cleaning, and as a precursor to other compounds. HEEDA is synthesized by reacting ethylenediamine with ethylene oxide. It is a colorless liquid that is soluble in water. HEEDA is studied because of its ability to complex with metals and its potential use in a variety of applications, including the development of new pharmaceuticals and pesticides.'
N-(2-hydroxyethyl)ethylenediamine: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 8112 |
| CHEMBL ID | 3186403 |
| SCHEMBL ID | 18854 |
| SCHEMBL ID | 2787111 |
| MeSH ID | M0109553 |
| Synonym |
|---|
| BIDD:GT0276 |
| 2-(2-aminoethylamino)ethanol |
| 2-((aminoethyl)amino)ethanol |
| n-aminoethylethanolamine |
| hsdb 2067 |
| ethanolethylene diamine |
| 1-(2-(hydroxyethyl)amino)-2-aminoethane |
| nsc 461 |
| ccris 4825 |
| (beta-hydroxyethyl)ethylenediamine |
| hydroxyethyl ethylenediamine |
| n-(beta-hydroxyethyl)ethylenediamine |
| ai3-15368 |
| einecs 203-867-5 |
| 2-((2-aminoethyl)amino)ethanol |
| ethanol, 2-((2-aminoethyl)amino)- |
| beta-aminoethyl-beta-hydroxyethylamine |
| n-aminoethyl ethanolamine |
| brn 0506012 |
| n-(2-hydroxyethyl)ethylenediamine |
| n-(aminoethyl)ethanolamine |
| 111-41-1 |
| n-(.beta.-aminoethyl)ethanolamine |
| nsc461 |
| wln: z2m2q |
| ethanol, 2-[(2-aminoethyl)amino]- |
| aminoethylethanolamine |
| 1-[2-(hydroxyethyl)amino]-2-aminoethane |
| monoethanolethylenediamine |
| (2-hydroxyethyl)ethylenediamine |
| (2-aminoethyl)ethanolamine |
| nsc-461 |
| n-(hydroxyethyl)ethylenediamine |
| n-hydroxyethyl-1,2-ethanediamine |
| n-(2-hydroxyethyl)-1,2-ethanediamine |
| 2-[(2-aminoethyl)amino]ethanol |
| n-(2-aminoethyl)ethanolamine |
| .beta.-aminoethyl-.beta.-hydroxyethylamine |
| (.beta.-hydroxyethyl)ethylenediamine |
| n-(.beta.-hydroxyethyl)ethylenediamine |
| inchi=1/c4h12n2o/c5-1-2-6-3-4-7/h6-7h,1-5h |
| n-(2-hydroxyethyl)ethylenediamine, 99% |
| A0299 |
| n-(2-hydroxyethyl)-ethylenediamine |
| 2-[2-aminoethylamino]ethanol |
| STK802366 |
| NCGC00248562-01 |
| tox21_200209 |
| dtxcid105423 |
| cas-111-41-1 |
| dtxsid7025423 , |
| NCGC00257763-01 |
| rc78w6npxt , |
| unii-rc78w6npxt |
| n-hydroxyethylethylenediamine |
| ec 203-867-5 |
| 4-04-00-01558 (beilstein handbook reference) |
| 2-[(2-aminoethyl)amino]ethan-1-ol |
| FT-0629139 |
| AKOS009156720 |
| 2-(2-hydroxyethylamino)ethylamine |
| 2-[(2-aminoethyl)amino]-ethanol |
| n-hydroxyethyl ethylene diamine |
| n-(2-hydroxy ethyl)ethylenediamine |
| (hydroxyethyl)ethylenediamine |
| n-(2-aminoethyl)-ethanolamine |
| n-(2-hydroxyethyl)ethylendiamine |
| n-(beta-hydroxyethyl)-ethylenediamine |
| n-(2-hydroxy ethyl) ethylenediamine |
| 2-(2-aminoethylamino)-ethanol |
| n-(beta-aminoethyl) ethanolamine |
| 2-(2-aminoethylamino) ethanol |
| BBL027690 |
| SCHEMBL18854 |
| hydroxyethylethylenediamine, n- |
| aminoethyl ethanolamine [hsdb] |
| aminoethylethanolamine [inci] |
| SCHEMBL2787111 |
| n-(2'-hydroxyethyl)ethylenediamine |
| 1-aminoethyl ethanolamine |
| 2-amino-2'-hydroxydiethylamine |
| n-.beta.-hydroxyethylethylenediamine |
| Q-200137 |
| CHEMBL3186403 |
| F0001-0240 |
| mfcd00008170 |
| aminoethylethanolamin |
| VS-08576 |
| Q209289 |
| CS-W011299 |
| D77720 |
| A935986 |
| EN300-126824 |
| Excerpt | Reference | Relevance |
|---|---|---|
| " GHS covers many aspects of effects upon health and the environment, including adverse effects upon sexual function and fertility or on development." | ( Guidance on classification for reproductive toxicity under the globally harmonized system of classification and labelling of chemicals (GHS). Boogaard, PJ; Bremer, S; Buesen, R; Edwards, J; Fraysse, B; Hallmark, N; Hemming, H; Hennes, C; Langrand-Lerche, C; McKee, RH; Meisters, ML; Moore, NP; Parsons, P; Politano, V; Reader, S; Ridgway, P, 2013) | 0.39 |
| Excerpt | Relevance | Reference |
|---|---|---|
| " Paris, France), in which groups of Wistar rats (10/sex/group) were administered the test substance by gavage at dosage levels of 50, 250, or 1000 mg/kg/day (groups 2-4, respectively)." | ( Malformations of the great vessels in the neonatal rat induced by N-(2-aminoethyl)ethanolamine. Moore, NP; Schneider, S; Treumann, S, 2012) | 0.38 |
| " A grading system for the dose-response of DAA lesions associated with AEEA by gavage was established." | ( Dissecting aortic aneurysm induced by N-(2-aminoethyl) ethanolamine in rat: Role of defective collagen during development. Boor, PJ; Rossbacher, R; Schneider, S; Treumann, S; Xu, Y, 2014) | 0.4 |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 34.7611 | 0.0006 | 57.9133 | 22,387.1992 | AID1259377 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (34.51) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (8.33%) | 6.00% |
| Case Studies | 1 (8.33%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 10 (83.33%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||