Compounds > n(5)-methyl-n(5)-formyl-2,5,6-triamino-4-hydroxypyrimidine
Page last updated: 2024-10-15

n(5)-methyl-n(5)-formyl-2,5,6-triamino-4-hydroxypyrimidine

Description

N(5)-methyl-N(5)-formyl-2,5,6-triamino-4-hydroxypyrimidine: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

2,6-diamino-4-hydroxy-5-(N-methylformamido)pyrimidine : A pyrimidine derivative having amino substituents in the 2- and 6-positions, a hydroxy substituent at the 4-position and an N-methylformamido group at the 5-position. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID135398708
CHEBI ID28643
SCHEMBL ID4620712
SCHEMBL ID8495863
MeSH IDM0112994

Synonyms (21)

Synonym
77440-13-2
mftahp
2,6-diamino-4-hydroxy-5-(n-methyl)formamidopyrimidine
C04744
CHEBI:28643
n-(2,4-diamino-6-hydroxypyrimidin-5-yl)-n-methylformamide
2,6-diamino-4-hydroxy-5-(n-methylformamido)pyrimidine
formamide, n-(2,6-diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-n-methyl-
n(5)-methyl-n(5)-formyl-2,5,6-triamino-4-hydroxypyrimidine
2,6-diamino-4-hydroxy-5-n-methylformamidopyrimidine
SCHEMBL4620712
2,6-diamino-4-hydroxy-5n-methyl-formamidopyrimidine
SCHEMBL8495863
me-fapygua
n5-methyl-n5-formyl-2,5,6-triamino-4-hydroxypyrimidine
n-(2,4-diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)-n-methyl-formamide
2,6-diamino-4-hydroxy- 5- formamidopyrimidine
Q27103805
n-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-n-methylformamide
n-(6-amino-4-hydroxy-2-imino-1,2-dihydropyrimidin-5-yl)-n-methylformamide
DTXSID60998651
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (3)

ClassDescription
aminopyrimidineA member of the class of pyrimidines that is pyrimidine substituted by at least one amino group and its derivatives.
formamidopyrimidine
hydroxypyrimidine
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (50.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
1,2-dimethylhydrazine
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.. 1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.		1.9610hydrazinesalkylating agent;
carcinogenic agent
dimethylnitrosamine
Dimethylnitrosamine: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties. It causes serious liver damage and is a hepatocarcinogen in rodents.		1.9610nitrosaminegeroprotector;
mutagen
dimethyl sulfate
dimethyl sulfate: RN given refers to unlabeled cpd; structure. dimethyl sulfate : The dimethyl ester of sulfuric acid.		1.9710alkyl sulfatealkylating agent;
immunosuppressive agent
methylnitrosourea
Methylnitrosourea: A nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.. N-methyl-N-nitrosourea : A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by methyl and nitroso groups.		1.9610N-nitrosoureasalkylating agent;
carcinogenic agent;
mutagen;
teratogenic agent
dimethylhydrazines
Dimethylhydrazines: Hydrazines substituted with two methyl groups in any position.		1.9610
guanine
[no description available]		2.38202-aminopurines;
oxopurine;
purine nucleobase		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
7-methylguanine
7-methylguanine: RN given refers to unlabeled cpd; structure. 7-methylguanine : A methylguanine that is guanine substituted by a methyl group at position 7. It is a metabolite obtained during the methylation of DNA.. 2-imino-7-methyl-1,2,3,7-tetrahydro-6H-purin-6-one : A 7-methylguanine that is 1,2,3,7-tetrahydro-6H-purin-6-one substituted by an imino group at position 2 and a methyl group at position 7.. 2-amino-7-methyl-7H-purin-6-ol : A 7-methylguanine that is 7H-purine substituted by an amino group at position 2, a methyl group at position 7 and a hydroxy group at position 6.. 2-amino-7-methyl-1,7-dihydro-6H-purin-6-one : A 7-methylguanine that is 1,7-dihydro-6H-purin-6-one substituted by an amino group at position 2 and a methyl group at position 7.		1.97107-methylguanine
8-hydroxyguanine
7,8-dihydro-8-oxoguanine: was substituted for guanine at G(8), G(9), G(14), or G(15) in the human telomeric oligonucleotide 5'-d[AGGGTTAG(8)G(9)GTT AG(14)G(15)GTTAGGGTGT]-3'. 7,8-dihydro-8-oxoguanine : An oxopurine that is guanine in which the hydrogen at position 8 is replaced by an oxo group and in which the nitrogens at positions 7 and 9 each bear a hydrogen.		1.9910oxopurine
methylnitronitrosoguanidine
Methylnitronitrosoguanidine: A nitrosoguanidine derivative with potent mutagenic and carcinogenic properties.. N-methyl-N'-nitro-N-nitrosoguanidine : An N-nitroguanidine compound having nitroso and methyl substituents at the N'-position		1.9710nitroso compoundalkylating agent
ConditionIndicatedRelationship StrengthStudiesTrials