Page last updated: 2024-12-06

myristyldimethylamine oxide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Myristyldimethylamine oxide (MDAO) is a cationic surfactant commonly used in personal care products. It is synthesized by reacting myristyl alcohol with dimethylamine in the presence of a catalyst. MDAO is known for its excellent foaming and cleaning properties. Its mildness on the skin and hair has led to its widespread use in shampoos, body washes, and other personal care products. Research on MDAO focuses on its effectiveness as a surfactant, its potential to cause irritation or allergic reactions, and its environmental impact. The study of MDAO is important for ensuring the safety and effectiveness of personal care products. Its biodegradability and low environmental toxicity make it a more sustainable choice compared to some other surfactants.'

myristyldimethylamine oxide: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID18739
CHEMBL ID1782221
SCHEMBL ID55872
MeSH IDM0508012

Synonyms (37)

Synonym
myristamine oxide
3332-27-2
dimethyl(tetradecyl)amine oxide
1-tetradecanamine, n,n-dimethyl-, n-oxide
n,n-dimethyltetradecan-1-amine oxide
CHEMBL1782221
n,n-dimethyltetradecylamine n-oxide
myristyldimethylamine oxide
ec 222-059-3
tetradecyldimethylamine oxide
tetradecanamine, n,n-dimethyl-, n-oxide
n,n-dimethyl-1-tetradecanamine-n-oxide
einecs 222-059-3
j086pm3rrt ,
unii-j086pm3rrt
n,n-dimethylmyristylamine n-oxide
myristyl dimethyl amine oxide
incromine oxide m
myristamine oxide [inci]
ammonyx mco
barlox 14
chemoxide mo-pf surfactant
empigen oh25
SCHEMBL55872
ONHFWHCMZAJCFB-UHFFFAOYSA-N
n,n-dimethyl-n-tetradecyl amine oxide
W-109885
n,n-dimethyl-1-tetradecanamine n-oxide
DTXSID2029660
myristyl dimethylamine oxide
n,n-dimethyltetradecylamine n-oxide, >=98.0% (nt)
n,n-dimethyltetradecylamine-n-oxide
CS-0256381
Q6948278
hc-pre
pre-dip additive
HY-W250186
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID599184Cytotoxicity at rat RBL2H3 cells assessed as maximum tolerated concentration by lactate dehydrogenase release assay2011European journal of medicinal chemistry, Jun, Volume: 46, Issue:6
Lipid-like sulfoxides and amine oxides as inhibitors of mast cell activation.
AID599182Inhibition of anti-DNP-IgE-induced degranulation in rat RBL2H3 cells assessed as beta-hexosaminidase release at 25 uM after 30 mins by fluorescence assay2011European journal of medicinal chemistry, Jun, Volume: 46, Issue:6
Lipid-like sulfoxides and amine oxides as inhibitors of mast cell activation.
AID599183Inhibition of anti-DNP-IgE-induced degranulation in rat RBL2H3 cells assessed as beta-hexosaminidase release after 30 mins by fluorescence assay2011European journal of medicinal chemistry, Jun, Volume: 46, Issue:6
Lipid-like sulfoxides and amine oxides as inhibitors of mast cell activation.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.79

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.79 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.73 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.79)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]